Glycosphingolipids Signaling

Cheorl-Ho Kim (Autor)

Buch | Hardcover

181 Seiten

2021 | 1st ed. 2020
Springer Verlag, Singapore
978-981-15-5806-1 (ISBN)

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This book presents the latest knowledge and the most recent research results on glycosphingolipid (GSL)-mediated signaling. GSLs are important constituents of the plasma membrane that exert their distinct functions through binding to certain functional proteins. They play a role in various human diseases and also function as human alloantigens. Cellular GSLs are associated with many biological functions such as cellular oncotransformation, phenotype change, neuronal or embryonic development, regulation of cell division, cell–cell interaction, cell attachment, adhesion, and motility, and intracellular signaling via protein–carbohydrate or carbohydrate–carbohydrate interactions. This book opens by providing the key background on GSL glycan–receptor interactions and mammalian GSL synthesis. Up-to-date information is then presented on all aspects of GSL-dependent signaling. Viral protein and bacterial toxin protein interactions with host cell GSLs are examined in depth, and the concluding chapter is devoted to signaling regulation. The book should assist in the further development of new strategies against emerging infectious agents and intractable diseases.

Prof. Cheorl-Ho Kim Molecular and Cellular Glycobiology Unit, Department of Biological Sciences, Sungkyunkwan University

1. Glycosphingolipids (GSLs).- 2. Mammal GSL synthesis via ER and Golgi network.- 3. The GSL dependent signaling.- 4. Viral protein interaction with host cells GSLs.- 5. Bacterial toxin protein interaction with host cells GSL.- 6. GSL signaling regulation.

Erscheinungsdatum	29.01.2021
Zusatzinfo	25 Illustrations, color; 5 Illustrations, black and white; XVII, 181 p. 30 illus., 25 illus. in color.
Verlagsort	Singapore
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
ISBN-10	981-15-5806-X / 981155806X
ISBN-13	978-981-15-5806-1 / 9789811558061
Zustand	Neuware