Pharmaceutical Crystals

Etsuo Yonemochi, Hidehiro Uekusa (Herausgeber)

Buch | Softcover

148 Seiten

2020
MDPI (Verlag)
978-3-03928-712-3 (ISBN)

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The crystalline state is the most commonly used essential solid active pharmaceutical ingredient (API). The characterization of pharmaceutical crystals encompasses many scientific disciplines, but the core is crystal structure analysis, which reveals the molecular structure of essential pharmaceutical compounds. Crystal structure analysis provides important structural information related to the API's wide range of physicochemical properties, such as solubility, stability, tablet performance, color, and hygroscopicity. This book entitled “Pharmaceutical Crystals" focuses on the relationship between crystal structure and physicochemical properties. In particular, the new crystal structure of pharmaceutical compounds involving multi-component crystals, such as co-crystals, salts, and hydrates, and polymorph crystals are reported. Such crystal structures were investigated in the latest studies that combined morphology, spectroscopic, theoretical calculation, and thermal analysis with crystallographic study. This book highlights the importance of crystal structure information in many areas of pharmaceutical science and presents current trends in the structure–property study of pharmaceutical crystals. The Guest Editors of this book hope the readers enjoy a wide variety of recent studies on Pharmaceutical Crystals.

Erscheinungsdatum	20.04.2020
Verlagsort	Basel
Sprache	englisch
Maße	170 x 244 mm
Themenwelt	Naturwissenschaften ► Chemie ► Allgemeines / Lexika
Schlagworte	1H-indole • 3,5-dihydro-4H-pyrimido[5,4-b]indol-4-one • adefovir dipivoxil • Benzodioxole • Carbamazepine • cocrystal • cocrystal formation • crystal habit • crystal structure • Crystal structure analysis • Dehydration • DFT • DFT study • dicarboxylic acid • Dissolution • Famotidine • famoxadone • HBV • Hepatitis B • Hirshfeld surface analysis • HOMO-LUMO • Hydrate • Hydrogen bond • hydrogen-bond-acceptance ability • Hydrogen Bonding • hygroscopicity • Imidazole • liquid assisted grinding • malonic acid • melting diagram • molecular docking study • N/A • Nitrofurantoin–4-dimethylaminopyridine (NF-DMAP) salt • Ondansetron • on-line monitoring • pharmaceutical cocrystal • pharmaceutical crystals • photostability • Physicochemical properties • Polymorphs • pyrimidin-4(3H)-one • Raman spectroscopy • reactivity descriptors • Saccharin • salt optimization • Semicarbazone • Solubility • solution crystallization • solvent-mediated polymorphic transformation • structure determination from powder diffraction data • succinic acid • Ticagrelor
ISBN-10	3-03928-712-5 / 3039287125
ISBN-13	978-3-03928-712-3 / 9783039287123
Zustand	Neuware