Homologation Reactions
Wiley-VCH (Verlag)
978-3-527-34815-2 (ISBN)
Vittorio Pace is holder of a TT Professorship in Drug Synthesis at the University of Vienna. He graduated in Pharmacy in 2005 from the University of Perugia (Italy) and subsequently, received the PhD in Chemical Sciences cum laude from the Complutense University of Madrid in 2010 working with Profs. Alcántara and Sinisterra. After postdoctoral training at Vienna (Prof. Holzer, 2010-2011), Manchester (Prof. Procter, 2011-2013) and Stockholm (Prof. Olofsson, 2013-2014), he obtained a group leader position at the University of Vienna in 2014. In 2016 he received the Habilitation (venia docendi et legendi) in Pharmaceutical Chemistry from the University of Vienna working on developing homologation strategies for rapidly assembling scaffolds of potential medicinal interest. In 2017 he obtained the Habilitation for Full Professor of Organic Chemistry granted by the Italian Ministry of University. He received several awards including the Ciamician Medal of the Italian Chemical Society, the Caglioti Prize of the Accademia Nazionale dei Lincei, the Young Investigator Award of the Faculty of Life Sciences at Vienna, the La Roche-Hoffmann Prize of the European Society of Medicinal Chemistry, the Viennese Innitzer Award in 2017, the Habilitation Award of the Austrian Chemical Society in 2019 and the Thieme Journal Award in 2020. He acts as Associate Editor of Monatshefte für Chemie - Chemical Monthly and is a board member of Molecules. His research core is represented by the design and development of novel homologative chemoselective transformations with functionalized organolithiums.
Foreword
Preface
Acknowledgments
VOLUME I
1 Diazo-Mediated Homologation Reactions
2 Lithium Carbenoids in Homologation Chemistry
3 Streamlining C1 Homologation Reactions Using Continuous Flow Technology: Focus on Diazomethane and Methyllithium Chemistry
4 Magnesium Carbenoids in Homologation Chemistry
5 Homologation Reactions Based on Zinc Carbenoids and Related Reagents
6 Homologations via Carbene-Mediated Rearrangement Reactions
7 Oxenoids as Homologation Partners
8 Sulfur Ylides as C1 Homologating Reagents
9 Modern Homologation Reactions of Sulfoxonium Ylides via C-H Activation
10 Phosphorus Reagents for Two-, Three-, and Four-Carbon Homologation of Carbonyl Compounds to Functionalized Olefins
11 Homologation Tactics with Diborylmethane via alpha-Boryl Carbanions
VOLUME II
12 Homologation of Boronic Acids and Organoboranes by Transition-Metal-Free Reactions with Diazo Compounds and N-Sulfonylhydrazones
13 Stereospecific Reagent-Controlled Homologation Using Carbenoids Generated by Sulfoxide-Metal Exchange
14 Iterative Homologation of Boronic Esters: Assembly Line Synthesis
15 Fluorocarbon Chain Homologation and Elongation Reactions
16 Homologation Reactions for the Synthesis of Fluorinated Molecules
17 Synthesis of Oxiranes and Aziridines from Aldehydes and Imines Using Anionic Homologation Approaches
18 One-Carbon Homologation and Homologation-Functionalization Reactions of Aldehydes
19 Ring Expansion Homologation: Synthetic Strategies and Reaction Design
20 Dehomologations and Ring Contraction Strategies
21 Direct Radical C1 Homologations
22 Allenation of Terminal Alkynes for Allene Synthesis
23 Homogeneous Carbon Monoxide Homologation
24 Homologation Reactions with Carbon Dioxide
Index
| Erscheinungsdatum | 21.06.2023 |
|---|---|
| Verlagsort | Weinheim |
| Sprache | englisch |
| Maße | 170 x 244 mm |
| Gewicht | 2142 g |
| Themenwelt | Naturwissenschaften ► Chemie ► Organische Chemie |
| Schlagworte | Chemie • Chemistry • Industrial Chemistry • Methods - Synthesis & Techniques • Organic Chemistry • Organische Chemie • Organische Chemie / Methoden, Synthesen, Verfahren • Pharmaceutical & Medicinal Chemistry • Pharmazeutische u. Medizinische Chemie • Technische u. Industrielle Chemie |
| ISBN-10 | 3-527-34815-8 / 3527348158 |
| ISBN-13 | 978-3-527-34815-2 / 9783527348152 |
| Zustand | Neuware |
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