Introduction To Immunotoxicology

Jacques Descotes (Autor)

Buch | Hardcover

183 Seiten

1998
Taylor & Francis Ltd (Verlag)
978-0-7484-0306-6 (ISBN)

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This text provides a concise and comprehensive introduction to key immunotoxicological issues for all those interested in, but with no prior knowledge of, this area of toxicology. The first section explores the health consequences of immunotoxicity, namely the adverse effects related to chemically-induced immunosuppression and immunostimulation, hypersensitivity reactions and autoimmune diseases, with an overview of major immunotoxicants. The second part describes the latest methods used to detect and evaluate, preclinically and clinically, the unexpected immunotoxic effects of xenobiotics. Trends in implementing strategies and recent changes to the regulatory aspects are also considered. The third section examines possible future developments, including In Vitro methods, biomarkers of immunotixicity and risk assessment.

Jacques Descotes

IMMUNOTOXIC EFFECTS AND THEIR CLINICAL CONSEQUENCES. Definition of Immunotoxicology 2. Overview of the Immune System. Immunosuppression and Immunodepression. Immunostimulation. Hypersensitivity. Autoimmunity. Major Immunotoxicants. IMMUNOTOXICITY EVALUATION. Guidelines. Histopathology. Assays of Humoral Immunity. Assays of Cell-Mediated Immunity. Assays of Non-Specific Defences. Host Resistance Assays. Strategies for the Evaluation of Immunosuppression. Identification of Chemical Sensitisers. Prediction of Autoimmunity. Trends and Perspectives in Immunotoxicology. Immunotoxicity Risk Assessment. New Methods in Immunotoxicology. Human Immunotoxicology. Immunotoxicology and Wildlife.

Erscheint lt. Verlag	9.12.1998
Verlagsort	London
Sprache	englisch
Maße	178 x 254 mm
Gewicht	521 g
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	0-7484-0306-X / 074840306X
ISBN-13	978-0-7484-0306-6 / 9780748403066
Zustand	Neuware