Sex Hormone Receptor Signals in Human Malignancies

Buch | Softcover

152 Seiten

2019
MDPI (Verlag)
978-3-03921-173-9 (ISBN)

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Sex steroids, including androgens, estrogens, and progestogens, are knownto have widespread physiological actions beyond the reproductive systemvia binding to the sex hormone receptors. Meanwhile, emerging evidence hasindicated that sex hormone receptor signals are involved in the outgrowth ofsome malignancies, such as prostate and breast carcinomas, as well as othersthat have not traditionally been considered as endocrine-related neoplasms. ThisSpecial Issue “Sex Hormone Receptor Signals in Human Malignancies” coversvarious aspects of the potential role of sex hormone receptors and related signalsin prostate cancer, breast cancer, and other neoplastic conditions by depictingpromising findings derived from in vitro and in vivo experiments as well as theanalyses of surgical specimens. The current observations described may thusprovide a unique insight into novel or known functions of sex hormone receptorsand related molecules.

Erscheinungsdatum	10.10.2019
Verlagsort	Basel
Sprache	englisch
Maße	170 x 244 mm
Themenwelt	Naturwissenschaften ► Biologie ► Allgemeines / Lexika
Themenwelt	Naturwissenschaften ► Biologie ► Humanbiologie
Schlagworte	Androgen deprivation therapy • androgen receptor • Breast Cancer • castration-resistant prostate cancer • COBRA1 • CRPC • drug screening and proteomics • ELK1 • Epidermal growth factor receptor • Estrogen • Estrogen Receptor • estrogen receptor alpha • ethinylestradiol • fibroblasts • FOXA1 • G-protein coupled estrogen receptor • heterogeneous nuclear ribonucleoprotein K • immunohistochemistry • Keratinocytes • levonorgestrel • Melanocytes • melanoma • mutational profiling • N/A • NELFB • nuclear factor erythroid 2-related factor 2 • ovarian cancer • PI3K pathway • progesterone receptor negative • prognosis • salivary gland tumors • sex hormone receptors • therapeutic targets • TP53 • Ultraviolet Radiation • upper urinary tract urothelial carcinoma
ISBN-10	3-03921-173-0 / 3039211730
ISBN-13	978-3-03921-173-9 / 9783039211739
Zustand	Neuware