Multiparticulate Oral Drug Delivery

Buch | Softcover

496 Seiten

2019
CRC Press (Verlag)
978-0-367-40204-4 (ISBN)

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This definitive reference explores the various aspects of multiparticulate dosage form development-assessing the in vivo behavior and performance of multiparticulates as well as comparing their market position to other dosage forms.
Discussing-for the first time in a comprehensive manner-alternative pelletization techniques such as balling (spherical agglomeration), spray congealing, and cryopelletization, Multiparticulate Oral Drug Delivery

describes formulation and processing variables that affect the formation, integrity, and performance of coatings derived from molten materials and polymeric solutions and dispersions

analyzes the biopharmaceutical aspects and in vivo performance of multiparticulate drug delivery systems

details the idiosyncrasies of the manufacturing process of hard-shell gelatin capsules

explains the different kinds of packaging materials and machinery and the importance of packaging during the development phase and beyond

previews the marketing considerations of multiparticulate systems in the years to come

presents practical solutions to problems encountered in the area of film-coating processes

and more!

Isaac Ghebre-Sellassie

Manufacture of Core Pellets by Balling
Preparation of Micropellets by Spray Congealing
Cryopelletization
Coating of Multiparticulates Using Polymeric Solutions: Formulation and Process Considerations
Coating of Multiparticulates Using Polymeric Dispersions: Formulation and Process Considerations
Coating of Multiparticulates Using Molten Materials: Formulation and Process Considerations,
Suspensions and Dispersible Dosage Forms of Multiparticulates, Roland Bodmeier and Ornlaksana Paeratakul
Multiparticulate Encapsulation Equipment and Process
Compaction of Multiparticulate Oral Dosage Forms
Key Factors in the Development of Modified-Release Pellets
Mechanisms of Release from Coated Pellets
Biopharmaceutical Aspects of Multiparticulates
In Vivo Behavior of Multiparticulate Versus Single-Unit Dose Formulations
Capsule Shell Composition and Manufacturing
Packaging of Multiparticulate Dosage Forms: Materials and Equipment
Marketing Considerations

Erscheinungsdatum	24.09.2019
Verlagsort	London
Sprache	englisch
Maße	152 x 229 mm
Gewicht	453 g
Themenwelt	Medizin / Pharmazie ► Pharmazie
	Naturwissenschaften ► Biologie
	Technik
ISBN-10	0-367-40204-1 / 0367402041
ISBN-13	978-0-367-40204-4 / 9780367402044
Zustand	Neuware