Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants, Two Volume Set
Seiten
2018
Wiley-Blackwell (Hersteller)
978-1-119-32972-5 (ISBN)
Wiley-Blackwell (Hersteller)
978-1-119-32972-5 (ISBN)
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Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided.
- Covers both basic science and applied technology / methods
- Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects
- Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development
- Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria
- Covers both basic science and applied technology / methods
- Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects
- Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development
- Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria
Yvonne Will, PhD, is a Senior Director and the Head of Science and Technology Strategy, Drug Safety Research and Development at Pfizer, Connecticut, USA. In addition to the prior edition of this book, she co-edited Drug Discovery Toxicology: From Target Assessment to Translational Biomarkers(Wiley, 2016). James A. Dykens, PhD, oversees EyeCyte Therapeutics, a start-up developing treatments for progressive blinding diseases via targeting mitochondrial dysfunction. He co-edited the first edition of this book.
| Erscheint lt. Verlag | 23.2.2018 |
|---|---|
| Verlagsort | Hoboken |
| Sprache | englisch |
| Maße | 150 x 250 mm |
| Gewicht | 666 g |
| Themenwelt | Naturwissenschaften ► Biologie |
| Naturwissenschaften ► Chemie | |
| ISBN-10 | 1-119-32972-8 / 1119329728 |
| ISBN-13 | 978-1-119-32972-5 / 9781119329725 |
| Zustand | Neuware |
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