Antidepressants

From Biogenic Amines to New Mechanisms of Action

Matthew Macaluso, Sheldon H. Preskorn (Herausgeber)

Buch | Hardcover

XII, 442 Seiten

2019 | 1st ed. 2019
Springer International Publishing (Verlag)
978-3-030-10948-6 (ISBN)

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This volume reviews the known neurobiology of depression and combines classic data on antidepressant treatments with modern theory on the physiology of depression. It also discusses novel mechanism of action drugs.

Part 1: Overview and General Principles.- 1. Impact, Diagnosis, Phenomenology, and Biology.- Part 2: The Past - from antiquity to 1970 including TCAs and MAOIs.- 2. Tricyclic Antidepressants and Monoamine Oxidase Inhibitors: Are They Too Old for a New Look?.- Part 3: The Present- 1970 to 2016.- 3. Clinical Implications of the STAR*D Trial.- 4. Pharmacogenomics and Biomarkers of Depression.- 5. Therapeutic Drug Monitoring of Antidepressants.- 6. Selective Serotonin Reuptake Inhibitors.- 7. Serotonin and Norepinephrine Reuptake Inhibitors.- 8. Neurostimulation Therapies.- 9. Current Role of Herbal and Natural Preparations.- Part 4: The future.- 10. Role of Inflammation in Depression and Treatment Implications.- 11. NMDA Antagonists for Treatment-Resistant Depression.- 12. Drug Development in Psychiatry: The Long and Winding Road from Chance Discovery to Rational Development.- 13. Other Antidepressants.- Part 5: Use of Antidepressants in Special Populations.- 14. Use of Antidepressants in Patients with Co-occurring Depression and Substance Use Disorders.- 15. Treatment of Depression in Women.- 16. Management of Late-Life Depression.- 17. The Use of Antidepressants in Bipolar Depression.

Erscheinungsdatum	21.06.2019
Reihe/Serie	Handbook of Experimental Pharmacology
Zusatzinfo	XII, 442 p. 17 illus., 8 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	841 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Psychiatrie / Psychotherapie
	Medizin / Pharmazie ► Pharmazie
	Naturwissenschaften ► Biologie ► Humanbiologie
	Naturwissenschaften ► Biologie ► Zoologie
Schlagworte	Clinical Trials • Mood Disorders • Novel mechanism of action drugs • Psychopharmacology • Treatment resistant depression
ISBN-10	3-030-10948-8 / 3030109488
ISBN-13	978-3-030-10948-6 / 9783030109486
Zustand	Neuware