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Heart Genomics -

Heart Genomics (eBook)

Hong Jiang, Ming Liu (Herausgeber)

eBook Download: PDF
2018 | 1st ed. 2018
VI, 374 Seiten
Springer Singapore (Verlag)
978-981-13-1429-2 (ISBN)
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This book elucidates how advances in genomics research are being applied in connection with heart diseases. It describes the development of genome-scale technologies and their applications to all areas of cardiac investigations, such as genomics, functional genomics, epigenomics, etc., and how they relate to a series of important breakthroughs in various heart diseases. Applying unbiased genomics, combined with a disease-focused and hypothesis-driven approach, represents a promising way to advance our understanding of cardiac diseases. The book offers an important reference work on introducing genomics in heart disease for all scientists and graduate students whose work involves genomics and cardiology, as well as for clinical physicians.



Dr. Hong Jiang is a Professor of Cardiology, Director of Science & Research, Fudan University Zhongshan Hospital; Shanghai leading talents?Director member of Shanghai health industry development & promotion association -Chronic Diseases Management specialist society?Deputy Director of Shanghai Institute of Clinical Bioinformatics, Deputy Director of Fudan University Center for Clinical Bioinformatics, Fudan University Zhongshan Hospital, Shanghai, China.

Dr. Ming Liu is a general practitioner, Secretary of Shanghai health industry development & promotion association -Chronic Diseases Management specialist society, Fudan University Zhongshan Hospital, Shanghai, China.



This book elucidates how advances in genomics research are being applied in connection with heart diseases. It describes the development of genome-scale technologies and their applications to all areas of cardiac investigations, such as genomics, functional genomics, epigenomics, etc., and how they relate to a series of important breakthroughs in various heart diseases. Applying unbiased genomics, combined with a disease-focused and hypothesis-driven approach, represents a promising way to advance our understanding of cardiac diseases. The book offers an important reference work on introducing genomics in heart disease for all scientists and graduate students whose work involves genomics and cardiology, as well as for clinical physicians.

Dr. Hong Jiang is a Professor of Cardiology, Director of Science & Research, Fudan University Zhongshan Hospital; Shanghai leading talents,Director member of Shanghai health industry development & promotion association -Chronic Diseases Management specialist society,Deputy Director of Shanghai Institute of Clinical Bioinformatics, Deputy Director of Fudan University Center for Clinical Bioinformatics, Fudan University Zhongshan Hospital, Shanghai, China. Dr. Ming Liu is a general practitioner, Secretary of Shanghai health industry development & promotion association -Chronic Diseases Management specialist society, Fudan University Zhongshan Hospital, Shanghai, China.

Genome-wide association studies of hypertension and several other cardiovascular diseases.- Cardiac transcriptome profile in heart diseases.- The Emerging Role of Epigenetics.- Mitochondria Genome Mutations and Cardiovascular Diseases.- GATA Transcription Factors and Cardiovascular Disease.- The Genetic Paradigm of WT1 Gene in Heart Development and Cardiac Repair.- Progress of genomics in hypertension-cardiac hypertrophy.- Progress of genomics in atherosclerosis-coronary heart disease and myocardial infarction.- Progress of genomics in cardiac conduction and rhythm disorders.- Progress of epigenetic changes in heart failure.- Progress of genetics in inherited cardiomyopathies-induced heart failure.- Warfarin and its pharmacogenomic study.- Gene therapy and genomic application in heart disease.

Erscheint lt. Verlag 11.10.2018
Reihe/Serie Translational Bioinformatics
Translational Bioinformatics
Zusatzinfo VI, 374 p. 11 illus., 7 illus. in color.
Verlagsort Singapore
Sprache englisch
Themenwelt Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Studium 2. Studienabschnitt (Klinik) Humangenetik
Naturwissenschaften Biologie
Schlagworte Cardiology • genome-scale technologies • Genome-wide association study • Genomic applications • Heart Diseases
ISBN-10 981-13-1429-2 / 9811314292
ISBN-13 978-981-13-1429-2 / 9789811314292
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