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Genetic Toxicology

Buch | Hardcover

504 Seiten

1991
Crc Press Inc (Verlag)
978-0-8493-8815-6 (ISBN)

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Genetic Toxicology is a comprehensive book covering the historical perspective of genetic toxicology; basic mechanisms of mutations and chromosomal effects; health consequences of genetic damage, including cancer and inheritable mutations; properties of physical, chemical, and biological mutagens; risk assessment of human exposure to genotoxicants; and the current position of some government regulatory agencies in the United States on the issues of genetic toxicology. The book will be a useful reference for students and researchers in toxicology, genetics, cancer biology, and medicine who are interested in the basic and applied principles of genetic toxicology. It will also benefit industrial toxicologists, products registration specialists, and government regulatory specialists with responsibility for the safety evaluation of industrial and environmental agents.

Introduction: Historical Perspectives of Genetic Toxicology. Mechanisms of Gene Mutations. Mechanisms of Induction of Chromosomal Alterations and Sister Chromatid Exchanges: Presentation of a Generalized Hypothesis. Germinal Mutation and Human Genetic Disease. Mutations and Cancer. Assays for Genetic Toxicity. Chemical Mutagens. Physical Mutagens. Biological Mutagens. Environmental Mutagens/Complex Mixtures. Mutagens in Foods. Antimutagens. Environmental Monitoring. Using Genetic Bioassays. Human Population Monitoring. Risk Assessment. Use of Mutagenicity Data By the U.S. Environmental Protection Agency's Office of Pesticide Programs. Regulatory Perspectives: TSCA. Regulatory Perspectives-FDA. Index.

Erscheint lt. Verlag	27.3.1991
Zusatzinfo	37 Tables, black and white
Verlagsort	Bosa Roca
Sprache	englisch
Maße	152 x 229 mm
Gewicht	839 g
Einbandart	gebunden
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie
Themenwelt	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
ISBN-10	0-8493-8815-5 / 0849388155
ISBN-13	978-0-8493-8815-6 / 9780849388156
Zustand	Neuware