Genes VI
Oxford University Press (Verlag)
978-0-19-857779-9 (ISBN)
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This text gives an integrated account of the structure and function of genes in both prokaryotic and eukaryotic organisms. It begins with an introductory overview of material that the student should have encountered in previous courses. There follows a detailed examination of the role and function of DNA. The third part of the book discusses translation and has been thoroughly up-dated to reflect new knowledge. The sections on gene expression have also been modernized and updated. The book concludes with chapters examining in detail the role of genes in some of the key areas of molecular cell biology research, development and oncogenesis. This text intended for undergraduates and research students following courses in: genetics; cell biology; molecular biology; biochemistry; microbiology; virology; and preclinical medicine.
After obtaining his degrees at the University of Cambridge, Dr. Benjamin Lewin was the founding editor of the journal cell, now one of the leading international journals in life science. As editor of cell, he is concerned with reviewing current research in molecular and cellular biology. In addition to writing Genes VI, he is the author of a three-volume series of advanced books on Gene expression.
Introduction: cells as macromolecular assemblies; proteins; compartments. Part 1: DNA as information; genes are mutable units; DNA is the genetic material; nucleic acid structure; isolating the gene. Part 2: from gene to protein; messenger RNA; protein synthesis; interpreting the genetic code; protein localization. Part 3: prokaryotic gene expression; transcription; the operon; phage strategies. Part 4: perpetuation of DNA; the replicon; DNA replication; restriction and repair; recombination; transposons; retroviruses and retroposons. Part 5: the eukaryotic genome; DNA biotechnology; genomes; exons and introns; gene numbers; organelle genomes; simple sequence DNA; chromosomes; nucleosomes. Part 6: eukaryotic gene expression; initiation of transcription; regulation of transcription; nuclear splicing; catalytic RNA; rearrangement of DNA; immune diversity. Part 7: cell growth, cancer, and development; protein trafficking; signal transduction; cell cycle and growth regulation; oncogenes and cancer; gradients and cascades. Epilogue: landmark shifts in perspective.
| Erscheint lt. Verlag | 31.3.1997 |
|---|---|
| Zusatzinfo | colour illustrations |
| Verlagsort | Oxford |
| Sprache | englisch |
| Themenwelt | Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| ISBN-10 | 0-19-857779-6 / 0198577796 |
| ISBN-13 | 978-0-19-857779-9 / 9780198577799 |
| Zustand | Neuware |
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