Albumin in Medicine

Pathological and Clinical Applications

Masaki Otagiri, Victor Tuan Giam Chuang (Herausgeber)

Buch | Softcover

277 Seiten

2018 | Softcover reprint of the original 1st ed. 2016
Springer Verlag, Singapore
978-981-10-9531-3 (ISBN)

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This book presents a comprehensive overview of medical and pharmaceutical applications of human serum albumin (HSA), with updates on structural aspects of albumin from the perspectives of X-ray crystallography and NMR, endogenous and exogenous ligand binding of albumin in various pathological conditions, and genetic variants and their phenotypes. Rapid progress and development of its applications have resulted in outstanding results for which albumin has clearly been proven to be a robust biomaterial. Contributions from leading international experts in this field show how HSA is applied to diagnosis, therapy, drugs, and treatment, with a comprehensive introduction of HSA. This volume will appeal to scientists in pharmaceutical and medical research including pharmaceutical chemists, pharmacokineticists, toxicologists, and biochemists not only in academia but also in industry. Readers can effectively acquire the most recent knowledge of applications of HSA and its impact on human health in a single volume.

Masaki Otagiri, Ph.D.Faculty of Pharmaceutical Sciences, Sojo University, Japan Victor Tuan Giam ChuangSchool of Pharmacy, Faculty of Health Sciences, Curtin University, Australia

PREFACE.-CONTRIBUTORS.-Chapter 1 Human Serum Albumin: A Multifunctional Protein.-Chapter 2 Stability of Albumin and Stabilization of Albumin Preparations.-Chapter 3 Albumin as a Biomarker.-Chapter 4 Albumin Fusion Protein.-Chapter 5 Albumin Nanoparticles.-Chapter 6 Nanoparticle Albumin Bound Paclitaxel (Abraxane®).-Chapter 7 OptisonTM Albumin Microspheres in Ultrasound Assisted Gene Therapy and Drug Delivery.-Chapter 8 S-Nitroso Adducts of Albumin Analogs: Characterization, Categorization, and Possible Future Therapeutic Applications.-Chapter 9 Hemoglobin-Albumin Clusters as a Red Blood Cell Substitute.-Chapter 10 The Influence of FcRn on Albumin-fused and Targeted Drugs.-Chapter 11 Human Serum Albumin in Blood Detoxification Treatment.-BIBLIOGRAPHY.-INDEX.

Erscheinungsdatum	27.08.2018
Zusatzinfo	37 Illustrations, color; 13 Illustrations, black and white; X, 277 p. 50 illus., 37 illus. in color.
Verlagsort	Singapore
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Pharmazie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Chemie ► Organische Chemie
Schlagworte	Disease treatment • Drug Delivery Systems • genetic variants • Ligand binding • Pathological conditions • Serum albumin
ISBN-10	981-10-9531-0 / 9811095310
ISBN-13	978-981-10-9531-3 / 9789811095313
Zustand	Neuware