Protein Crystallography
Humana Press Inc. (Verlag)
978-1-4939-8363-6 (ISBN)
Authoritative and practical, Protein Crystallography aims to ensure successful results in the further study of this vital field.
Expression and Purification of Recombinant Proteins in Escherichia Coli with a His6 or Dual His6-MBP Tag.- Protein Crystallization.- Advanced Methods of Protein Crystallization.- The ‘Sticky Patch’ Model of Crystallization and Modification of Proteins for Enhanced Crystallizability.- Crystallization of Membrane Proteins: and Overview.- Locating and Visualizing Crystals for X-ray Diffraction Experiments.- Collection of X-ray Diffraction Data from Macromolecular Crystals.- Identifying and Overcoming Crystal Pathologies: Disorder and Twinning.- Applications of X-ray Micro-beam for Data Collection.- Serial Synchrotron X-ray Crystallography (SSX).- Time-Resolved Macromolecular Crystallography at Modern X-ray Sources.- Structure Determination Using X-ray Free-electron Laser Pulses.- Processing of XFEL Data.- Many Ways to Derivatize Macromolecules and their Crystals for Phasing.- Experimental Phasing: Substructure Solution and Density Modification as Implemented in SHELX.- Contemporary Use of Anomalous Diffraction in Biomolecular Structure Analysis.- Long-Wavelength X-ray Diffraction and its Applications in Macromolecular Crystallography.- Acknowledging Errors: Advanced Molecular Replacement with Phaser.- Rosetta Structure Prediction as a Tool for Solving Difficult Molecular Replacement Problems.- Radiation Damage in Macromolecular Crystallography.- Boxes of Model Building and Visualization.- Structure Refinement at Atomic Resolution.- Low Resolution Refinement of Atomic Models against Crystallographic Data.- Stereochemistry and Validation of Macromolecular Structures.- Validation of Protein-Ligand Crystal Structure Models: Small Molecule and Peptide Ligands.- Protein Data Bank - the Single Global Macromolecular Structure Archive Managed by the Worldwide Protein Data Bank.- Databases, Repositories and Other Data Resources in Structural Biology.
| Erscheinungsdatum | 18.08.2018 |
|---|---|
| Reihe/Serie | Methods in Molecular Biology ; 1607 |
| Zusatzinfo | 145 Illustrations, color; 28 Illustrations, black and white; XIII, 672 p. 173 illus., 145 illus. in color. |
| Verlagsort | Totowa, NJ |
| Sprache | englisch |
| Maße | 178 x 254 mm |
| Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
| Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
| Schlagworte | macromolecular crystallography • Macromolecules • Multicrystal S-SAD • Purification • XFEL |
| ISBN-10 | 1-4939-8363-6 / 1493983636 |
| ISBN-13 | 978-1-4939-8363-6 / 9781493983636 |
| Zustand | Neuware |
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