Physicochemical and Biomimetic Properties in Drug Discovery (eBook)

Chromatographic Techniques for Lead Optimization, Enhanced Edition

Klara Valko (Autor)

eBook Download: EPUB

2014 | 1. Auflage
450 Seiten
John Wiley & Sons (Verlag)
978-1-118-81744-5 (ISBN)

Infos

Demonstrating how and why to measure physicochemical and biomimetic properties in early stages of drug discovery for lead optimization, Physicochemical and Biomimetic Properties in Drug Discovery encourages readers to discover relationships between various measurements and develop a sense of interdisciplinary thinking that will add to new research in drug discovery. This practical guide includes detailed descriptions of state-of-the-art chromatographic techniques and uses real-life examples and models to help medicinal chemists and scientists and advanced graduate students apply measurement data for optimal drug discovery.

Autor

KLARA VALKO is an Investigator in the Analytical Chemistry Department of Molecular Discovery Research at GlaxoSmithKline. Dr. Valko has more than thirty years of experience in HPLC, GC, and LC/MS. She also has more than ten years of experience teaching physicochemical measurements and ADME optimization tools at the UCL School of Pharmacy. Currently, Dr. Valko is an Honorary Professor, leading the Physchem/ADME module for a drug discovery MSc course.

Rezensionen

"This is one of those books that will not gather dust on the shelf (barring an epochal revolution in the field) because it will be a constant point of reference for established scientists participating in multidisciplinary pharmaceutical research teams or those who wish to establish themselves in this area." (Doody's, 16 January 2015)

Produkt-Details

• Erscheint lt. Verlag: 29.1.2014
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Chemie ► Physikalische Chemie
• Schlagworte: Chemie • Chemistry • Chromatographie / Trennverfahren • Chromatography / Separation Techniques • Physical Chemistry • Physical Chemistry of Drugs • Physikalische Chemie • Physikalische Chemie in der Pharmazie
• ISBN-10: 1-118-81744-3 / 1118817443
• ISBN-13: 978-1-118-81744-5 / 9781118817445