Oxidation of C-H Bonds (eBook)

Wenjun Lu, Lihong Zhou (Autoren)

eBook Download: EPUB

2017 | 1. Auflage
528 Seiten
John Wiley & Sons (Verlag)
978-1-119-09250-6 (ISBN)

Infos

A combination of oxidation methods and CH bond functionalization, this book emphasizes mechanistic understanding and critical analysis of synthetic reactions to offer a guide or manual for practicing chemists.

* Combines oxidation methods and CH bond functionalization, two of the most important aspects of organic synthesis
* Deals with CH bonds, an area of dynamic and continuous research across chemistry and catalysis
* Helps readers understand the fundamental and applied differences among various oxidation methods and reactions
* Covers mechanistic details, conditions, oxidation reagents, and practical aspects of different reactions

Autor

Wenjun Lu, D.Eng., is a Professor of Organic Chemistry at Shanghai Jiao Tong University. Lihong Zhou, PhD, is a Research Associate at Shanghai Jiao Tong University.

Inhalt

1 Introduction 1

1.1 What Is Oxidation of C??H Bonds? 1

1.2 Chemical Synthesis and Oxidation of C??H Bonds 2

1.3 C??H Bonds 6

1.4 Concepts in This Book 15

References 17

2 Oxidation of Methane 19

2.1 Methane 19

2.2 Methyl sp3 C??H Bond 20

2.3 Oxidations of Methyl sp3 C??H Bond 21

2.4 Summary 35

References 36

3 Oxidation of Alkyl sp3 C??H Bond 39

3.1 Alkane 39

3.2 Alkyl sp3 C??H Bonds 40

3.3 Oxidations of Alkyl sp3 C??H Bond 42

3.4 Summary 61

References 62

4 Oxidation of Alkyl sp3 C??H Bond Assisted by Directing Group 65

4.1 Directing Group 65

4.2 Alkyl sp3 C??H Bonds with Directing Groups 66

4.3 Directed Oxidations of Alkyl sp3 C??H Bond 67

4.4 Summary 97

References 97

5 Oxidation of Alkyl sp3 C--H Bond Adjacent to Unsaturated Carbon Atom 101

5.1 Alkyl alpha?]sp3 C??H Bond 101

5.2 Alkyl sp3 C??H Bonds Adjacent to Unsaturated Carbon Atoms 102

5.3 Oxidations of Alkyl sp3 C??H Bond Adjacent to Unsaturated Carbon Atom 103

5.4 Summary 138

References 138

6 Oxidation of Alkyl sp3 C??H Bond Adjacent to Heteroatom 143

6.1 Alkyl sp3 C??H Bonds Adjacent to Heteroatoms 143

6.2 Oxidations of Alkyl sp3 C??H Bond Adjacent to Heteroatom 144

6.3 Summary 166

References 167

7 Oxidation of Alkenyl or Carbonyl sp2 C??H Bond 171

7.1 Alkenyl and Carbonyl sp2 C??H Bonds 171

7.2 Oxidations of Alkenyl and Carbonyl sp2 C??H Bonds 172

7.3 Summary 203

References 204

8 Oxidation of Alkynyl spC??H Bond 209

8.1 spC??H Bonds 209

8.2 Oxidations of spC??H Bond 210

8.3 Summary 232

References 232

9 Oxidation of Benzene 235

9.1 Introduction 235

9.2 Oxidations of Phenyl sp2 C??H Bond 237

9.3 Summary 277

References 279

10 Oxidation of Aryl sp2 C??H Bond on Substituted Benzene 283

10.1 Introduction 283

10.2 Formation of C??C Bond 284

10.3 Formation of C??N Bond 313

10.4 Formation of C??O Bond 316

10.5 Formation of C??S Bond 322

10.6 Formation of C??Halogen Bond 323

10.7 Summary 331

References 333

11 Oxidation of Aryl sp2 C??H Bond Assisted by Directing Group 337

11.1 Introduction 337

11.2 Formation of C??C Bond 337

11.3 Formation of C??N Bond 400

11.4 Formation of C??O Bond 406

11.5 Formation of C??S Bond 412

11.6 Formation of C??Halogen Bond 414

11.7 Summary 424

References 426

12 Oxidation of Aryl sp2 C??H Bond on Heteroarene or Perfluoroarene 433

12.1 Introduction 433

12.2 Formation of C??C Bond 434

12.3 Formation of C??N Bond 459

12.4 Formation of C??O Bond 461

12.5 Formation of C??Halogen Bond 462

12.6 Cross?]Coupling of Dual Aryl sp2 C??H Bonds on Directing?]Group?]Containing Arenes, Heteroarenes,

or Polyfluoroarenes 468

12.7 Summary 477

References 478

13 Oxidative Cross?]Coupling of Aryl sp2 C??H Bond with Inert C??H Bond 483

13.1 Introduction 483

13.2 Oxidative Coupling of Simple Arenes with Alkanes (Alkylation of Arenes) 484

13.3 Oxidative Coupling of Simple Arenes with Alkenes (Alkenylation of Arenes) 486

13.4 Oxidative Cross?]Coupling of Simple Arenes (Arylation of Arenes) 490

13.5 Summary 498

References 499

Index 501

Produkt-Details

• Erscheint lt. Verlag: 27.2.2017
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Chemie ► Organische Chemie
• Themenwelt: Naturwissenschaften ► Chemie ► Technische Chemie
• Themenwelt: Technik
• Schlagworte: catalysis • Chemie • Chemistry • Katalyse • Methods - Synthesis & Techniques • Organische Chemie / Methoden, Synthesen, Verfahren • Physical Chemistry • Physikalische Chemie
• ISBN-10: 1-119-09250-7 / 1119092507
• ISBN-13: 978-1-119-09250-6 / 9781119092506