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Macrolides

Properties, Synthesis and Applications
Buch | Hardcover
VIII, 104 Seiten
2018
De Gruyter (Verlag)
978-3-11-051502-2 (ISBN)
CHF 146,90 inkl. MwSt
Macrolide antibiotics represent a class of natural macrocyclic products, one of the most clinically important antibiotics. Unfortunately, the production and development of new macrolide antibiotics are not represented enough in the pharmaceutical industry today. The intention of the book is therefore not only to be a teaching tool for students and experts, but also to draw the attention of the general public to this extremely useful, cheap and relatively unharmful effective anti-macrobials, and potential anti-malarials. The authors introduce the different classes of macrolides and their derivatives, principles of their biological activity, their structure and interactions with biological targets as well as synthetic methods to produce new macrolide antibiotics of similar or improved properties. Special emphasis was put on conjugates of macrolides with nucleobases or nucleosides with numerous applications; among them the most important remains the attempt to overcome bacterial resistance.

Macrolide antibiotics represent a class of natural macrocyclic products, one of the most clinically important antibiotics. Unfortunately, the production and development of new macrolide antibiotics are not represented enough in the pharmaceutical industry today. The intention of the book is therefore not only to be a teaching tool for students and experts, but also to draw the attention of the general public to this extremely useful, cheap and relatively unharmful effective anti-microbials, and potential anti-malarials. The authors introduce the different classes of macrolides and their derivatives, principles of their biological activity, their structure and interactions with biological targets as well as synthetic methods to produce new macrolide antibiotics of similar or improved properties. Special emphasis was put on conjugates of macrolides with nucleobases or nucleosides with numerous applications; among them the most important remains the attempt to overcome bacterial resistance.

Biljana Arsic, University of Nis, Nis, Republic of Serbia.

Erscheinungsdatum
Zusatzinfo 50 b/w and 15 col. ill., 2 b/w tbl.
Verlagsort Berlin/Boston
Sprache englisch
Maße 170 x 240 mm
Gewicht 361 g
Themenwelt Naturwissenschaften Chemie Organische Chemie
Schlagworte Antibiotikum • Makrocyclische Verbindungen • Makrolidantibiotikum • Makrolide
ISBN-10 3-11-051502-4 / 3110515024
ISBN-13 978-3-11-051502-2 / 9783110515022
Zustand Neuware
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