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Protein Engineering Techniques -  Khushboo Gulati,  Krishna Mohan Poluri

Protein Engineering Techniques (eBook)

Gateways to Synthetic Protein Universe
eBook Download: PDF
2016 | 1st ed. 2017
XIV, 134 Seiten
Springer Singapore (Verlag)
978-981-10-2732-1 (ISBN)
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This brief provides a broad overview of protein-engineering research, offering a glimpse of the most common experimental methods. It also presents various computational programs with applications that are widely used in directed evolution, computational and de novo protein design. Further, it sheds light on the advantages and pitfalls of existing methodologies and future perspectives of protein engineering techniques.



Dr. Krishna Mohan Poluri is currently working as an Asst. Professor at the Department of Biotechnology, IIT-Roorkee. He completed his PhD in Chemistry from the Tata Institute of Fundamental Research TIFR-Mumbai, and Post-doc from Rutgers University. Dr. Poluri worked as a Research scientist at the University of Texas Medical Branch (UTMB-Texas). His areas of expertise are Protein Engineering, Bio-molecular Spectroscopy, Structural Biology, Molecular Biophysics, Bio-molecular Interactions, Glycoimmunology, Structural virology and Structure based design of Therapeutics and Scaffolds. He is an editorial member and reviewer for several journals. He has won several awards and fellowships for his research work. Most prominent being: Young scientist awards from Indian Science Congress association (ISCA) -2009, National Academy of Sciences India (NASI)-2014, and Innovative Young Biotechnologist Award (IYBA)-2013 by DBT.

Ms. Khushboo Gulati is currently pursuing her PhD at Department of Biotechnology, IIT- Roorkee. She completed her Bachelors in Bioinformatics and Masters in Biotechnology from Punjab University, India. Her Research interests are in the area of Protein Engineering, Molecular Biophysics, Structural Biology and Glycoimmunology including Protein Carbohydrate interactions.

This brief provides a broad overview of protein-engineering research, offering a glimpse of the most common experimental methods. It also presents various computational programs with applications that are widely used in directed evolution, computational and de novo protein design. Further, it sheds light on the advantages and pitfalls of existing methodologies and future perspectives of protein engineering techniques.

Dr. Krishna Mohan Poluri is currently working as an Asst. Professor at the Department of Biotechnology, IIT-Roorkee. He completed his PhD in Chemistry from the Tata Institute of Fundamental Research TIFR-Mumbai, and Post-doc from Rutgers University. Dr. Poluri worked as a Research scientist at the University of Texas Medical Branch (UTMB-Texas). His areas of expertise are Protein Engineering, Bio-molecular Spectroscopy, Structural Biology, Molecular Biophysics, Bio-molecular Interactions, Glycoimmunology, Structural virology and Structure based design of Therapeutics and Scaffolds. He is an editorial member and reviewer for several journals. He has won several awards and fellowships for his research work. Most prominent being: Young scientist awards from Indian Science Congress association (ISCA) -2009, National Academy of Sciences India (NASI)-2014, and Innovative Young Biotechnologist Award (IYBA)-2013 by DBT.Ms. Khushboo Gulati is currently pursuing her PhD at Department of Biotechnology, IIT- Roorkee. She completed her Bachelors in Bioinformatics and Masters in Biotechnology from Punjab University, India. Her Research interests are in the area of Protein Engineering, Molecular Biophysics, Structural Biology and Glycoimmunology including Protein Carbohydrate interactions.

World of Proteins: Structure-Function relationships and Engineering techniques.- Expanding the Synthetic Protein universe by guided Evolutionary Concepts.- Rationale Designing of Novel Proteins through Computational Approaches.- Generating the Fancy Protein Basket with De novo Approach.- Biotechnological Applications of Protein Engineering Methods.

Erscheint lt. Verlag 12.11.2016
Reihe/Serie SpringerBriefs in Applied Sciences and Technology
SpringerBriefs in Applied Sciences and Technology
SpringerBriefs in Forensic and Medical Bioinformatics
SpringerBriefs in Forensic and Medical Bioinformatics
Zusatzinfo XIV, 134 p. 37 illus. in color.
Verlagsort Singapore
Sprache englisch
Themenwelt Informatik Theorie / Studium Künstliche Intelligenz / Robotik
Medizin / Pharmazie Pflege
Medizin / Pharmazie Physiotherapie / Ergotherapie Orthopädie
Naturwissenschaften Biologie Biochemie
Technik Bauwesen
Technik Umwelttechnik / Biotechnologie
Schlagworte Computational Approaches to Protein Design • Protein Carbohydrate Interaction • Protein Drugs • Protein Evolution • Protein Folding • Protein Structure-function Relationship • Structural Virology • Structure Based Drug Design • Synthetic/Engineered Proteins • Therapeutic proteins
ISBN-10 981-10-2732-3 / 9811027323
ISBN-13 978-981-10-2732-1 / 9789811027321
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