Für diesen Artikel ist leider kein Bild verfügbar.

Anticandidal effect of azole derived from natural bioactive alcohol

Mohammad Irfan, Nikhat Manzoor, Mohammad Abid (Autoren)

Buch | Softcover

232 Seiten

2016
Scholars' Press (Verlag)
978-3-659-84356-3 (ISBN)

Titel nicht im Sortiment

Artikel merken

The increasing incidences of human candidiasis and its tendency to become resistant to existing chemotherapies is a well-recognised health problem. Most frequently Candida infection occur in the person having pre-clinical complications such as HIV positive, cancer therapy, organ transplantation, diabetes, week immunity, using corticosteroids and broad spectrum antibiotics. Antifungal drugs currently used for the treatment of Candida infections include polyenes, azoles, echinocandins, allyamines, and flucytosine. These drugs exert either fungicidal or fungistatic activities by interfering with essential cellular processes. For over last two decade, azoles have been a mainstay of the antifungal therapy. Additionally, various biological properties of triazoles such as antineoplastic, antibacterial, analgesic, anti-inflammatory, antimalarial, anticonvulsant, etc have been reported which prompt researchers to explore these pharmacophore. This study includes the synthesis of some novel 1,2,3-triazole derivatives and evaluation of their biological properties against Candida cells

Dr. Abid is working as Asstt. Prof. in the Deptt. of Biosciences, JMI, Delhi, India. Abid earned his Ph.D. in Chemistry from JMI. Post Ph.D., he joined Univ. Paris Descartes, France as a Postdoc. Recently, he has been awarded prestigious RAMAN Fellowship by UGC to carry out Research at Eppley Institute for Research in Cancer, UNMC, Omaha, USA.

Erscheinungsdatum	04.11.2016
Sprache	englisch
Maße	150 x 220 mm
Gewicht	362 g
Themenwelt	Naturwissenschaften ► Biologie ► Allgemeines / Lexika
Themenwelt	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
Schlagworte	1 • 2 • 3-triazoles • Candida • CYP51 • Cytotoxicity • fluconazole • Hemolysis • homology modeling • Natural bioactive alcohols • Scholar's Press
ISBN-10	3-659-84356-3 / 3659843563
ISBN-13	978-3-659-84356-3 / 9783659843563
Zustand	Neuware