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Cytoprotection and Cytobiolgy

Proceedings of the Ninth Symposium on Cytoprotection, Kyoto, March 2, 1991

K. Yunoki (Herausgeber)

Buch | Hardcover

300 Seiten

1992
Elsevier Science Ltd (Verlag)
978-0-444-89429-8 (ISBN)

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Biological homeostasis is maintained by protective mechanisms, involving local reactions in the injured tissue and whole body reactions. Overexpression of the protective mechanisms is, however, sometimes injurious to the organism. The Symposia on Cytoprotection are held annually to discuss cytoprotective mechanisms from both basic and clinical viewpoints. The topics of the presentations vary widely, from gastrointestinal mucosal disturbances, liver and pancreatic dysfunctions, cerebral ischemia, endothelial cell function to biochemical characteristics of cancer cells, and tissue damage produced by excessive production of superoxides and free radicals and protective procedures for such damage. In one of the two Special Lectures, Professor Kyoko Hotta reviewed recent results of biochemical studies of mucus glycoprotein and the relations between the protective functions and the structural properties of mucus.
Professor Shin-ichi Akiyama reported that multi-drug resistance is due to drug efflux resulting from a 170 kD membrane glycoprotein (P glycoprotein) and that agents that reverse multidrug resistance do so by competing with cytotoxic drugs for a binding site on P glycoprotein, the drug efflux pump. The concept of cytoprotection should be applied to protective mechanisms against various stresses in organisms. The results reported in this Proceedings will contribute to the further development of biochemical physiological research. Original reports are published as full papers. Papers that have appeared or will appear in other publications are published here as summaries.

Preface. I. Special lectures. Mucus and mucin: Fundamental aspects (Kyoko Hotta). The expression of P-glycoprotein in human tumors and mechanisms to overcome multidrug resistance (Shin-ichi Akiyama). II. Gastrointestinal mucosal injury (I) . Chairman's remarks (Yukio Nagamachi). 7 papers. III. Gastrointestinal mucosal injury (II) . Chairman's remarks (Norio Nakamura). 8 papers. IV. Liver and pancreas. Chairman's remarks (Takayoshi Tobe). 4 papers. V. Brain. Chairman's remarks (Hideo Mabe). 8 papers. VI. Metabolism in endothelial cells, connective tissue, and others. Chairman's remarks (Ikuro Maruyama). 6 papers. VII. Cancer cells and others. Chairman's remarks (Masaki Kitajima). 6 papers. VIII. Free radicals (I) . Chairman's remarks (Masaharu Tsuchiya). 6 papers. IX. Free radicals (II) . Chairman's remarks (Keiichi Kawai). 6 papers. Author index.

Reihe/Serie	Current Clinical Practice ; v. 62
Verlagsort	Oxford
Sprache	englisch
Gewicht	1000 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Gastroenterologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	0-444-89429-2 / 0444894292
ISBN-13	978-0-444-89429-8 / 9780444894298
Zustand	Neuware