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Comparative Gene Finding - Marina Axelson-Fisk

Comparative Gene Finding

Models, Algorithms and Implementation
Buch | Softcover
382 Seiten
2016 | Softcover reprint of the original 2nd ed. 2015
Springer London Ltd (Verlag)
978-1-4471-6875-1 (ISBN)
CHF 149,75 inkl. MwSt
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This book presents a guide to building computational gene finders, and describes the state of the art in computational gene finding methods, with a focus on comparative approaches. Fully updated and expanded, this new edition examines next-generation sequencing (NGS) technology. The book also discusses conditional random fields, enhancing the broad coverage of topics spanning probability theory, statistics, information theory, optimization theory and numerical analysis. Features: introduces the fundamental terms and concepts in the field; discusses algorithms for single-species gene finding, and approaches to pairwise and multiple sequence alignments, then describes how the strengths in both areas can be combined to improve the accuracy of gene finding; explores the gene features most commonly captured by a computational gene model, and explains the basics of parameter training; illustrates how to implement a comparative gene finder; examines NGS techniques and how to build a genome annotation pipeline.

Introduction.- Single Species Gene Finding.- Sequence Alignment.- Comparative Gene Finding.- Gene Structure Submodels.- Parameter Training.- Implementation of a Comparative Gene Finder.- Annotation Pipelines for Next Generation Sequencing Projects.

Erscheinungsdatum
Reihe/Serie Computational Biology ; 20
Zusatzinfo 81 Illustrations, black and white; XX, 382 p. 81 illus.
Verlagsort England
Sprache englisch
Maße 155 x 235 mm
Themenwelt Mathematik / Informatik Informatik Theorie / Studium
Informatik Weitere Themen Bioinformatik
Naturwissenschaften Biologie Genetik / Molekularbiologie
Schlagworte algorithms • Bioinformatics • Biological sequence analysis • comparative genomics • Computational Biology • Computational Gene Finding • genes • Genetics • Information Theory • sequence alignment
ISBN-10 1-4471-6875-5 / 1447168755
ISBN-13 978-1-4471-6875-1 / 9781447168751
Zustand Neuware
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