Complex Structure and Dynamics of the Heart

Philip Bittihn (Autor)

Buch | Softcover

XV, 204 Seiten

2016 | 1. Softcover reprint of the original 1st ed. 2015
Springer International Publishing (Verlag)
978-3-319-36385-1 (ISBN)

Artikel merken

This award-winning thesis investigates the mechanisms underlying cardiac arrhythmia development and termination from an entirely new perspective. By viewing the heart as a complex system, the author uses theoretical tools from nonlinear dynamics combined with numerical simulations and experiments to achieve insights into the relationship between its structure and dynamics, thereby paving the way towards innovative low-energy defibrillation strategies. The work tackles, among other things: the effect of substrate heterogeneity on the spatial-temporal dynamics of cardiac arrhythmias and ways in which weak pulsed electric fields can be used to control these dynamics in heterogeneous cardiac tissue. The long-term vision of this research is to replace the current strategy of applying painful and sometimes tissue damaging electric shock - currently the only reliable way to terminate life-threatening fibrillation - by a more subtle but equally effective intervention. The book maps out a number of promising research directions for biophysicists and medical researchers working on the origins and treatment of cardiac arrhythmias.

Dr. Philip Bittihn studied physics at the Georg-August-Universität Göttingen as a scholar of the Studienstiftung des deutschen Volkes (German National Academic Foundation). In 2009, he obtained his diploma with honors from the university, before joining the MPRG Biomedical Physics at the Max Planck Institute for Dynamics and Self-Organization, Göttingen. He received his PhD in June 2013 for theoretical and experimental work on the complex structure and dynamics of the heart and is currently a postdoctoral scholar at the BioCircuits Institute, University of California, San Diego. His interests include the nonlinear dynamics and emergent phenomena of biological systems, numerical simulations, partial differential equations and experimental data analysis.

Introduction.- Methods.- Results.- Conclusion.- Appendix A Modeling Details.- Appendix B Supplementary Data.- Appendix C MediaSim -- An Open Framework for Simulating Extended Systems.- Index.

Erscheinungsdatum	05.03.2022
Reihe/Serie	Springer Theses
Zusatzinfo	XV, 204 p. 69 illus., 47 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	340 g
Themenwelt	Naturwissenschaften ► Physik / Astronomie ► Angewandte Physik
Schlagworte	Applications of Nonlinear Dynamics and Chaos Theor • Biological and Medical Physics, Biophysics • Biophysics • Cardiac Dynamics • Cardiology • Cardiovascular medicine • Dynamics and statics • Electric-field-based Control Strategies • Fibrillation and Defibrillation • Heart as a Complex System • Heart Muscle as Excitable Medium • Mathematical Models of Cardiac Tissue • Mathematical Physics • medical physics • Nonlinear Science • Numerical and Computational Physics, Simulation • Numerical Simulations of Heart Dynamics • Physics • Physics and Astronomy
ISBN-10	3-319-36385-9 / 3319363859
ISBN-13	978-3-319-36385-1 / 9783319363851
Zustand	Neuware