Tumor Cell Metabolism

Pathways, Regulation and Biology

Sybille Mazurek, Maria Shoshan (Herausgeber)

Buch | Softcover

VIII, 374 Seiten

2016 | 1. Softcover reprint of the original 1st ed. 2015
Springer Wien (Verlag)
978-3-7091-1989-1 (ISBN)

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The four sections of this book cover cell and molecular biology of tumor metabolism, metabolites, tumor microenvironment, diagnostics and epigenetics. Written by international experts, it provides a thorough insight into and understanding of tumor cell metabolism and its role in tumor biology. The book is intended for scientists in cancer cell and molecular biology, scientists in drug and diagnostic development, as well as for clinicians and oncologists.

Metabolic Remodeling in Bioenergetic Disorders and Cancer .- Tumor Cell Complexity and Metabolic Flexibility.- Autophagy and Tumor Cell Metabolism.-Tumour Hypoxia and the Hypoxia-Inducible Transcription.- MYC Regulation of Metabolism and Cancer.- Pyruvate Kinase M2: A Metabolic Tuner.- Role of the Pentose Phosphate Pathway in Tumour Metabolism.- Enzymes of the Tumour Metabolome in Diagnostic Applications.- Contribution of pH Alterations to the Tumor Microenvironment.- Mitochondrial Mutations in Cancer Progression: Causative, Bystanders, or Modifiers of Tumorigenesis? The Relevance of the Mitochondrial H+-ATP Synthase.- Canceromics Studies Unravel Tumor's Glutamine Addiction.- Essential Role of Mitochondria in Pyrimidine Metabolism.- Metabolic Fluxes in Cancer Metabolism.- Targeted 13C-Labeled Tracer Fate Associations for Drug Efficacy Testing in Cancer.

Erscheinungsdatum	14.10.2016
Zusatzinfo	VIII, 374 p. 52 illus., 35 illus. in color.
Verlagsort	Vienna
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Medizin / Pharmazie ► Studium
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
Schlagworte	Biomedical and Life Sciences • Cancer Research • drug development • Energy metabolism • Medical Research • metabolic phenotype • Molecular Biology • Molecular Medicine • molecular signaling • Oncology • tumor cell biology • tumor cell metabolism
ISBN-10	3-7091-1989-8 / 3709119898
ISBN-13	978-3-7091-1989-1 / 9783709119891
Zustand	Neuware