Logic Synthesis for Genetic Diseases

Modeling Disease Behavior Using Boolean Networks

Pey-Chang Kent Lin, Sunil P. Khatri (Autoren)

Buch | Softcover

100 Seiten

2016 | Softcover reprint of the original 1st ed. 2014
Springer-Verlag New York Inc.
978-1-4939-5535-0 (ISBN)

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This book brings to bear a body of logic synthesis techniques, in order to contribute to the analysis and control of Boolean Networks (BN) for modeling genetic diseases such as cancer. The authors provide several VLSI logic techniques to model the genetic disease behavior as a BN, with powerful implicit enumeration techniques. Coverage also includes techniques from VLSI testing to control a faulty BN, transforming its behavior to a healthy BN, potentially aiding in efforts to find the best candidates for treatment of genetic diseases.

Introduction.- Part I Inference of Gene Regulatory Networks.- Predictor Set Inference using SAT.- Determining Gene Function in Boolean Networks using SAT.- Predictor Ranking using Modified Zhegalkin Functions.- Part II Intervention of Gene Regulatory Networks.- ATPG for Cancer Therapy.- Summary and Future Work.

Erscheinungsdatum	15.10.2016
Zusatzinfo	8 Illustrations, color; 20 Illustrations, black and white; XXI, 100 p. 28 illus., 8 illus. in color.
Verlagsort	New York
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Informatik ► Weitere Themen ► Bioinformatik
	Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie
	Naturwissenschaften ► Biologie
	Technik ► Elektrotechnik / Energietechnik
	Technik ► Medizintechnik
ISBN-10	1-4939-5535-7 / 1493955357
ISBN-13	978-1-4939-5535-0 / 9781493955350
Zustand	Neuware