Viral Vectors for Gene Therapy
Humana Press Inc. (Verlag)
978-1-4939-5828-3 (ISBN)
Comprehensive and practical, Viral Vectors for Gene Therapy: Methods and Protocols provides basic principles accessible to scientists from a wide variety of backgrounds for the development of gene therapy viral products that are safe and effective.
Introduction to Viral Vectors.- Introduction to Gene Therapy: A Clinical Aftermath.- Host Cells and Cell Banking.- Overview of Current Scalable Methods for Purification of Viral Vectors.- Methods to Construct Recombinant Adenovirus Vectors.- Manufacturing of Adenoviruses Vectors: Production and Purification of Helper Dependent Adenovirus.- Manufacturing of Retroviruses.- Lentiviral Vectors.- Adeno-Associated Viruses.- Manufacturing of Adeno-Associated Viruses, for Example: AAV2.- Vector Characterization Methods for Quality Control Testing of Recombinant Adeno-Associated Viruses.- Baculoviruses Mediate Efficient Gene Expression in a Wide Range of Vertebrate Cells.- Herpes Simplex Virus Type 1 (HSV-1)-Derived Recombinant and Amplicon Vectors.- Manufacture of Measles Viruses.- In Vivo Gene Delivery into hCD34+ Cells in a Humanized Mouse Model.- In Vivo Evaluation of Gene Transfer into Mesenchymal Cells (in View of Cartilage Repair).- Ethical Consideration.- Clinical Trials of GMP Products in the Gene Therapy Field.
Erscheinungsdatum | 11.08.2016 |
---|---|
Reihe/Serie | Methods in Molecular Biology ; 737 |
Zusatzinfo | 5 Illustrations, color; 57 Illustrations, black and white; XI, 450 p. 62 illus., 5 illus. in color. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Biomedizin |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin | |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
ISBN-10 | 1-4939-5828-3 / 1493958283 |
ISBN-13 | 978-1-4939-5828-3 / 9781493958283 |
Zustand | Neuware |
Haben Sie eine Frage zum Produkt? |
aus dem Bereich