Protein Therapeutics

Zuben E. Sauna, Chava Kimchi-Sarfaty (Herausgeber)

Buch | Hardcover

XIII, 182 Seiten

2017 | 1st ed. 2017
Springer International Publishing (Verlag)
978-3-319-41816-2 (ISBN)

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Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactionson the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors

Protein Production in Eukaryotic Cells.- Production of Protein Therapeutics in the Quality by Design (QbD) Paradigm.- Characterization of Therapeutic Proteins.- Immunogenicity Lessons Learned from the Clinical Development of Vatreptacog Alfa, A Recombinant Activated Factor VII Analog, in Hemophilia with Inhibitors.- The Art of Gene Redesign and Recombinant Protein Production: Approaches and Perspectives.

Erscheinungsdatum	04.08.2017
Reihe/Serie	Topics in Medicinal Chemistry
Zusatzinfo	XIII, 182 p.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Pharmazie
	Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie
	Medizin / Pharmazie ► Studium
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Chemie ► Physikalische Chemie
Schlagworte	Bio-betters • Bioengineering • biomedical engineering • Biosimilars • Chemistry and Materials Science • Factor IX-FC Fusion Protein • Factor VIIa Analogs • medicinal chemistry • monoclonal antibodies • Personalized medicine • Protein Science • Protein therapeutics • Quality-by-Design • Replacement Protein-therapeutics
ISBN-10	3-319-41816-5 / 3319418165
ISBN-13	978-3-319-41816-2 / 9783319418162
Zustand	Neuware