Injury Models of the Central Nervous System
Humana Press Inc. (Verlag)
978-1-4939-3814-8 (ISBN)
contain valuable information carefully chosen to widen the researchers’ horizon
about neurotrauma. Injury Models of Central Nervous System: Methods and Protocols contains relevant experimental design approaches that have been
adapted and made ready for application in laboratory settings. For easier
navigation, the chapters are categorized into 6 parts: Introduction, General
Consideration in Using Animal Laboratory in CNS Injury Research, Classical TBI
Models and Their Link with Pathophysiological Features of CBS Injury – Models,
Special Topics in CNS Trauma: Comorbid Conditions in CNS Injury, Outcome
Measures in Brain Injury Models, and Future Directions. Written in the highly successful Methods in
Molecular Biology series format, chapters include introductions to their
respective topics, lists of the necessary materials and reagents, step-by-step,
readily reproducible laboratory protocols, and tips on troubleshooting and
avoiding known pitfalls.
Practical and thorough, Injury Models of Central Nervous Systems: Methods and Protocols, is a very useful reference towards the
progress of this discipline.
The History and Evolution of
Experimental Traumatic Brain Injury Models.- Clinical Traumatic Brain Injury in
the Preclinical Setting.- Rodent
Models of Traumatic Brain Injury: Methods and Challenges.- Traumatic
Brain Injury Models in Animals.- Systematic
Review of Traumatic Brain Injury Animal Models.- Methods
of Drug Delivery in Neurotrauma.- Bridging
the Gap of Standardized Animals Models for Blast Neurotrauma: Methodology for Appropriate Experimental Testing.- Cellular
Mechanisms and Behavioral Outcomes in Blast-Induced Neurotrauma: Comparing
Experimental Set-Ups.- Application
of Systems Biology to Neuroproteomics: The Path to Enhanced Theranostics for
Traumatic Brain Injury.- Role of Systems Biology in Brain
Injury Biomarker Discovery: A Neuroproteomic Application.- The
Controlled Cortical Impact Model of Experimental Brain Trauma: Overview,
Research Applications, and Protocol.- Weight
Drop Models in Traumatic Brain Injury.- Midline
(Central) Fluid Percussion Model of Traumatic Brain Injury.- Lateral
(Parasagittal) Fluid Percussion Model of Brain Injury.- Impact
Acceleration Model of Diffuse Traumatic Brain Injury.- Experimental
Models for Neurotrauma Research.- A Porcine Model
of Traumatic Brain Injury via Head Rotational Acceleration.- Pediatric
Rodent Models of Traumatic
Brain Injury.- Modeling
Pediatric Brain Trauma: Piglet Model of Controlled Cortical Impact.- Thromboembolic
Model of Cerebral Ischemia and Reperfusion in Mice.- Animal
Stroke Model: Ischemia/Reperfusion and Intracerebral Hemorrhage.- Combined
Neurotrauma Models: Experimental Models Combining Traumatic Brain Injury and Secondary
Insults.- Microdialysis as Clinical
Evaluation of Therapeutic Hypothermia in Rat Subdural Hematoma Model.- Repetitive Transcranial Magnetic
Stimulation as a Novel Therapy in Animal Models of Traumatic Brain Injury.- Experimental
Models Combining TBI, Hemorrhagic Shock, and Hypoxemia.- Experimental
Models Combining Traumatic Brain Injury and Hypoxia.- Animal
Models of Post-Traumatic Seizures and Epilepsy.- Closed-Head
TBI Model of Multiple-Morbidity.- Cognitive
Evaluation Using Morris Water Maze in Neurotrauma.- Assessment
of Cognitive Function in the Water Maze Task: Maximizing Data Collection and Analysis
in Animal Models of Brain Injury.- Detecting
Behavioral Deficits Post Traumatic Brain Injury in Rats.- Advanced
and High Throughput Method for Mitochondrial Bioenergetics Evaluation in
Neurotrauma.- Determination
of Vascular Reactivity of Middle Cerebral Arteries from Stroke and Spinal Cord
Injury Animal Models Using Pressure Myography.- Assessment of Basilar Artery Reactivity
in Stroke and Subarachnoid Hemorrhage Using Wire Myograph.- Magnetic Resonance Imaging in Experimental
Traumatic Brain Injury.- A Simplified Workflow for Protein
Quantitation of Rat Brain Tissues Using Label-Free Proteomics and Spectral
Counting.- Phenotypic Screening of Small-Molecule
Inhibitors: Implications for Therapeutic Discovery and Drug Target Development
in Traumatic Brain Injury.- Postnatal Neural Stem Cells in
Treating Traumatic Brain Injury.- A Novel Biopsy Method for Isolating
Neural Stem Cells from the Subventricular Zone of the Adult Rat Brain for Autologous
Transplantation in CNS Injuries.- Challenging the Paradigms of Experimental
TBI Models: From Preclinical to Clinical Practice.
| Erscheinungsdatum | 11.10.2016 |
|---|---|
| Reihe/Serie | Methods in Molecular Biology ; 1462 |
| Zusatzinfo | 104 Illustrations, color; 53 Illustrations, black and white; XXIV, 743 p. 157 illus., 104 illus. in color. |
| Verlagsort | Totowa, NJ |
| Sprache | englisch |
| Maße | 178 x 254 mm |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie |
| Medizin / Pharmazie ► Studium | |
| Naturwissenschaften ► Biologie ► Humanbiologie | |
| Naturwissenschaften ► Biologie ► Zoologie | |
| Schlagworte | diffuse axonal injuries • Epilepsy • Hypoxemia • Hypoxia • mitochondrial bioenergetics • pediatric rodent models of TBI • pressure myography • Proteomics • Small molecule inhibitors • Stem Cell Therapy • traumatic brain injury (TBI) |
| ISBN-10 | 1-4939-3814-2 / 1493938142 |
| ISBN-13 | 978-1-4939-3814-8 / 9781493938148 |
| Zustand | Neuware |
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