The Nuclear Receptor Superfamily
Humana Press Inc. (Verlag)
978-1-4939-3722-6 (ISBN)
This
volume aims to describe a
complementary range of molecular, cell biological, and in vivo protocols used to investigate
the structure–function of nuclear receptors, together with experimental
approaches that may lead to new drugs to selectively target nuclear
receptor-associated diseases. The Nuclear
Receptor Superfamily, Second Edition will benefit those starting out in the
nuclear receptor research field as well as to more established researchers who
wish to apply different methods to a particular receptor or research problem.
Written in the highly successful Methods in Molecular Biology series
format, chapters include introductions to their respective topics, lists of the
necessary materials and reagents, step-by-step, readily reproducible laboratory
protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative
and cutting-edge, The Nuclear Receptor
Superfamily, Second Edition aims to ensure successful results in the
further study of this vital field.
The Nuclear Receptor Superfamily- At
Thirty.- Lipid Homeostasis and Ligands for
Liver X Receptors: Identification and Characterization.- Use
of Differential Scanning Fluorimetry to Identify Nuclear Receptor Ligands.- Drug-Discovery Pipeline for Novel
Inhibitors of the Androgen Receptor.- Use
of BRET to Study Protein-Protein Interactions in vitro and in vivo.- Studying
Steroid Receptor Complexes in the Cellular Environment.- Post-translational
Modifications of Steroid Receptors: Phosphorylation.- Mapping protein-DNA Interactions using ChIP-exo and Illumina-based Sequencing.- Methods to Identify
Chromatin Bound Protein Complexes: From Genome-Wide to Locus Specific Approaches.- Measuring the Expression of microRNAs Regulated by
Androgens.- Methods for Identifying and
Quantifying Mrna Expression of Androgen Receptor Splicing Variants in Prostate
Cancer.- Harvesting
Human Prostate Tissue Material and Culturing Primary Prostate Epithelial Cells.- In
vivo Imaging of Nuclear Receptor Transcriptional Activity.- Development
and Characterisation of Cell-Specific Androgen Receptor Knockout Mice.
| Erscheinungsdatum | 08.10.2016 |
|---|---|
| Reihe/Serie | Methods in Molecular Biology ; 1443 |
| Zusatzinfo | 32 Illustrations, color; 12 Illustrations, black and white; X, 250 p. 44 illus., 32 illus. in color. |
| Verlagsort | Totowa, NJ |
| Sprache | englisch |
| Maße | 178 x 254 mm |
| Themenwelt | Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie |
| Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| Schlagworte | cell biological • in vivo protocols • Nuclear receptors • proteins • structure–function of nuclear receptors • target nuclear receptor-associated diseases |
| ISBN-10 | 1-4939-3722-7 / 1493937227 |
| ISBN-13 | 978-1-4939-3722-6 / 9781493937226 |
| Zustand | Neuware |
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