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Quantifying Interactions of Biomolecules with Inorganic Surfaces

Abhijeet Patra (Autor)

Buch | Hardcover

XVIII, 102 Seiten

2016 | 1st ed. 2017
Springer International Publishing (Verlag)
978-3-319-30727-5 (ISBN)

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This thesis demonstrates the adaptation of existing techniques and principles towards enabling clean and precise measurements of biomolecules interacting with inorganic surfaces. In particular, it includes real-time measurement of serum proteins interacting with engineered nanomaterial. Making meaningful and unambiguous measurements has been an evolving problem in the field of biology and its various allied domains, primarily due to the complex nature of experiments and the large number of possible interferants. The subsequent quantification of interactions between biomolecules and inorganic surfaces solves pressing problems in the rapidly developing fields of lipidomics and nanomedicine.

Abhijeet Patra obtained his bachelors degree in Electrical and Electronics Engineering from the National Institute of Technology, Tiruchchirappalli, one of the premier institutes in India in 2011. Upon receiving the prestigious NGS scholarship to pursue doctoral studies at National University of Singapore, he joined the research group of Prof T Venkatesan, pioneer of pulsed laser deposition and, after an exciting 4 years, graduated with a PhD in 2015. His research interests are in understanding how inorganic assemblies interact with the biological world, with a sharp focus on translating the science into biomedical applications.

Introduction.- Methods.- Quantifying interactions between water and surfaces.- Quantifying interactions between lipids and surfaces.- Quantifying interactions between serum proteins and gold nanoparticles.- Conclusion.

Erscheinungsdatum	05.01.2017
Reihe/Serie	Springer Theses
Zusatzinfo	XVIII, 102 p. 39 illus., 35 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Naturwissenschaften ► Physik / Astronomie ► Atom- / Kern- / Molekularphysik
	Naturwissenschaften ► Physik / Astronomie ► Festkörperphysik
	Naturwissenschaften ► Physik / Astronomie ► Thermodynamik
	Technik ► Maschinenbau
Schlagworte	Lipid Fraction Enrichment • Measurement Science and Instrumentation • nanochemistry • Nanoparticle-Based Drug Screening • nanoscale science and technology • Nanoscale Wettability • Physics and Astronomy • Protein Corona • Serum Protein Interactions • Soft and Granular Matter, Complex Fluids and Micro • Surface Plasmon Resonance • Surfaces and Interfaces, Thin Films
ISBN-10	3-319-30727-4 / 3319307274
ISBN-13	978-3-319-30727-5 / 9783319307275
Zustand	Neuware