Activation-Induced Deaminase
On the Targeting Mechanism of AID to the Immunoglobulin Loci
Seiten
| Ausstattung: Hardcover & eBook
2019
De Gruyter
978-3-11-046075-9 (ISBN)
De Gruyter
978-3-11-046075-9 (ISBN)
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The mechanism of hypermutation, the process needed for B cell affinity maturation, is one of the last great mysteries in molecular biology. Activation-induced deaminase (AID) is absolutely required for hypermutation, but the mechanism by which it is recruited specifically to antibody-encoding genes remains enigmatic. This book summarizes the research on AID in the context of its central role in the affinity maturation of B cells.
Andrew Franklin, Berlin, Germany.
| Zusatzinfo | Includes a print version and an ebook |
|---|---|
| Verlagsort | Berlin |
| Sprache | englisch |
| Maße | 240 x 170 mm |
| Themenwelt | Naturwissenschaften ► Biologie |
| Schlagworte | Affinity maturation • Antibody • B cells • hypermutation • immune response |
| ISBN-10 | 3-11-046075-0 / 3110460750 |
| ISBN-13 | 978-3-11-046075-9 / 9783110460759 |
| Zustand | Neuware |
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