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Correlation Force Spectroscopy for Single Molecule Measurements

Milad Radiom (Autor)

Buch | Hardcover

XXVII, 117 Seiten

2015 | 2015
Springer International Publishing (Verlag)
978-3-319-14047-6 (ISBN)

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This thesis addresses the development of a new force spectroscopy tool, correlation force spectroscopy (CFS) for the measurement of the properties of very small volumes of material (molecular to µm³) at kHz-MHz frequency range. CFS measures the simultaneous thermal fluctuations of two closely-spaced atomic force microscopy (AFM) cantilevers. CFS then calculates the cross-correlation in the thermal fluctuations that gives the mechanical properties of the matter that spans the gap of the two cantilevers. The book also discusses development of CFS, its advantages over AFM, and its application in single molecule force spectroscopy and micro-rheology.

Milad Radiom received his PhD in Chemical Engineering at Virginia Tech in 2014, after MEng and BSc in Thermal and Fluids Engineering and Mechanical Engineering respectively from Nanyang Technological University and Amirkabir University of Technology. Thereafter, he was appointed as a postdoctoral research associate in Laboratory of Colloid and Surface Chemistry, University of Geneva. His research interests are physical chemistry of polymers, colloids and surfaces as related to single molecule force spectroscopy, micro-rheology and surface forces.

Introduction.- Correlation Force Spectroscopy.- Dynamics of Single Molecules.- Microrheology with Correlation Force Spectroscopy.- Development of Colloidal Probe Correlation Force Spectroscopy: Case Study.- Correlation Force Spectroscopy for Single Molecule Measurements.- Single Molecule Force Spectroscopy of Dextran.- Single Molecule Force Spectroscopy of Single-Stranded DNA.- Summary.

Erscheint lt. Verlag	14.4.2015
Reihe/Serie	Springer Theses
Zusatzinfo	XXVII, 117 p. 48 illus., 31 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Naturwissenschaften ► Chemie ► Analytische Chemie
	Naturwissenschaften ► Chemie ► Physikalische Chemie
	Naturwissenschaften ► Chemie ► Technische Chemie
	Naturwissenschaften ► Physik / Astronomie ► Atom- / Kern- / Molekularphysik
Schlagworte	Atomic force microscopy • Colloidal Probe Correlation Force • Correlation Force Spectroscopy • Single Molecule Force Spectroscopy • spectroscopy
ISBN-10	3-319-14047-7 / 3319140477
ISBN-13	978-3-319-14047-6 / 9783319140476
Zustand	Neuware