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Bone and Mineral Research Annual

J.N.M. Heersche, J. A. Kanis (Herausgeber)

Buch | Hardcover
324 Seiten
1994
Elsevier Science Ltd (Verlag)
978-0-444-89659-9 (ISBN)
CHF 267,95 inkl. MwSt
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This volume reviews the prevalence, pathophysiology and consequences of primary hyperparathryroidism, one of the most common endocrine disorders. It covers the role of vitamin D in disorders of proliferation and contains contributions on: bone remodelling, Sillience, and the bisphosphonates.
Although the regulation and mechanism of action of the major calcium regulating hormones (such as vitamin D and parathyroid hormone) have long been recognised, there are more important gaps in knowledge. This volume reviews the prevalence, patholophysiology and consequences of primary hyperparathyroidism, one of the most common endocrine disorders. It covers the potential role of vitamin D in disorders of proliferation, providing some thoughtful insights into the signals for parathyroid gland profileration and secretation, and making the important distinction between the two. The volume also contains contributions in the areas of: bone remodelling (including the cytokines and their regulation in physiology of bone call function, of bone disease; aspects of regulation of cartilage differentation and metabolism; and TGFB, one of the major non-collagenous cytokines in bone); the broad clinical classification of Sillience; and the bisphosphonates (including their use in Paget's disease, tumor induced bone disease, hyperpathyroidism and osteoporosis; and their structure, function, pharmacokinetic mechanism of action and the therapeutic implications.

Primary Hyperparathyroidism: Prevalence, Pathophysiology, Pertinent Findings and Prognosis (S. Ljunghall, J. Rastad, G. Akerstrom). Vitamin D and Cancers: New insight into Vitamin D Physiology and Potential for Cancer therapy (J.A. Eisman). Cytokines and Cellular interactions in the control Bone of Remodelling (M.. Gowen). Regulation of Cartilage Differentiation and Metabolism (F. Suzuki). Transforming Growth Factor-bs: Biological Activities Related to bone Metabolism (D.M. Rosen). Osteogenesis Imperfecta as a Consequence of Naturally Occuring and induced Mutations of Type I Collagen (W.G. Cole). Bisphosphonates in Clinical Medicine (J.-P Bonjour, R, Rizzoli, P. Amman, T. Chevalley). Bisphosphonates and Therapeutic Implications (A.D. Geddes, S.M. D'Souza, F.H. Ebetino, K.J. Ibbotson).

Reihe/Serie The bone & mineral research annual ; Vol 8
Verlagsort Oxford
Sprache englisch
Gewicht 810 g
Themenwelt Medizinische Fachgebiete Innere Medizin Endokrinologie
Studium 1. Studienabschnitt (Vorklinik) Anatomie / Neuroanatomie
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Naturwissenschaften Biologie Zoologie
ISBN-10 0-444-89659-7 / 0444896597
ISBN-13 978-0-444-89659-9 / 9780444896599
Zustand Neuware
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