Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease (eBook)

Mark Lyte, John F. Cryan (Herausgeber)

eBook Download: PDF

2014 | 2014
XVIII, 436 Seiten
Springer New York (Verlag)
978-1-4939-0897-4 (ISBN)

Infos

The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host ('us'). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.​

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The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host ("e;us"e;). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.?

Inhalt

Part I: Basic Concepts Underlying the Microbiota-Gut-Brain Axis.- Microbial Endocrinology and the Microbiota-Gut-Brain Axis.- Utilizing “omics” Tools to Study the Complex Gut Ecosystem.- The Enteric Nervous System and Gastrointestinal Innervation: Integrated Local and Central Control.- Intestinal Barrier Function and the Brain-Gut Axis.- Vagal Pathways for Microbiome-Brain-Gut Axis Communication.- The Brain-Gut Axis in Health and Disease.- Part II: Mechanistic Factors Influencing the Microbiota-Gut-Brain Axis.- Gastrointestinal Hormones and Their Targets.- Microbiome, HPA Axis and Production of Endocrine Hormones in the Gut.- Neuropeptides and the Microbiota‑Gut‑Brain Axis.- Bacterial Neuroactive Compounds Produced by Psychobiotics.- Multidirectional Chemical Signalling Between Mammalian Hosts, Resident Microbiota, and Invasive Pathogens:  Neuroendocrine Hormone-Induced Changes in Bacterial Gene Expression.- Influence of Stressor-Induced Nervous System Activation on the Intestinal Microbiota and the Importance for Immunomodulation.- Part III: The Microbiota-Gut-Brain Axis in Health and Disease.- The Effects of Inflammation, Infection and Antibiotics on the Microbiota-Gut-Brain Axis.- Microbiota, Inflammation and Obesity.- Microbiota, Immunoregulatory Old Friends and Psychiatric Disorders.- Microbiota-Gut-Brain Axis and Cognitive Function.- The Impact of Microbiota on Brain and Behavior: Mechanisms & Therapeutic Potential.- Neuroimaging the Microbiome-Gut–Brain Axis.- The Future of Probiotics for Disorders of the Brain-Gut Axis.- Index.

Produkt-Details

• Erscheint lt. Verlag: 5.7.2014
• Reihe/Serie: Advances in Experimental Medicine and Biology
• Reihe/Serie: Advances in Experimental Medicine and Biology
• Reihe/Serie: Microbial Endocrinology
• Reihe/Serie: Microbial Endocrinology
• Zusatzinfo: XVIII, 436 p. 48 illus., 19 illus. in color.
• Verlagsort: New York
• Sprache: englisch
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
• Themenwelt: Technik
• Schlagworte: Disease • microbial endocrinology • microbiome • Physiology
• ISBN-10: 1-4939-0897-9 / 1493908979
• ISBN-13: 978-1-4939-0897-4 / 9781493908974