Gasotransmitters: Physiology and Pathophysiology
Seiten
2014
|
2012
Springer Berlin (Verlag)
978-3-642-44652-8 (ISBN)
Springer Berlin (Verlag)
978-3-642-44652-8 (ISBN)
This richly illustrated expert review of the biological, pharmacological and medical functions of the signaling molecules nitric oxide, carbon monoxide, and hydrogen sulfide collates the impressive quantity of fresh data accumulated in recent years.
Since the epochal discovery of the radical and highly toxic gas nitric oxide (NO) as a signaling molecule, two other no less toxic gases - carbon monoxide (CO) and hydrogen sulfide (H 2 S) - have been found to also be involved in a plethora of physiological and pathophysiological functions. The gases termed gasotransmitters play an increasingly important role in understanding how signalling into and between cells is modulated and fine-tuned. The advent of gasotransmitters has profoundly changed our way of thinking about biosynthesis, liberation, storage and action mechanisms in cellular signaling. In recent years an impressive amount of new data, distributed throughout the existing literature, has been generated. For this book the editors have recruited distinguished colleagues in the field to summarize and review important biological, pharmacological and medical functions and their implications, as well as methods for the detection of gasotransmitters.
Since the epochal discovery of the radical and highly toxic gas nitric oxide (NO) as a signaling molecule, two other no less toxic gases - carbon monoxide (CO) and hydrogen sulfide (H 2 S) - have been found to also be involved in a plethora of physiological and pathophysiological functions. The gases termed gasotransmitters play an increasingly important role in understanding how signalling into and between cells is modulated and fine-tuned. The advent of gasotransmitters has profoundly changed our way of thinking about biosynthesis, liberation, storage and action mechanisms in cellular signaling. In recent years an impressive amount of new data, distributed throughout the existing literature, has been generated. For this book the editors have recruited distinguished colleagues in the field to summarize and review important biological, pharmacological and medical functions and their implications, as well as methods for the detection of gasotransmitters.
Nitric Oxide: Biological Synthesis and Functions.- The Role of Carbon Monoxide as a Gasotransmitter in Cardiovascular and Metabolic Regulation.- Physiological and Pathophysiological Functions of Hydrogen Sulfide.- Methods for the Detection of Gasotransmitters.- Gasotransmitters in Regulation of Neuromuscular Transmission.- Modulated by Gasotransmitters - BK Channels.
| Erscheint lt. Verlag | 9.8.2014 |
|---|---|
| Zusatzinfo | X, 206 p. |
| Verlagsort | Berlin |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 338 g |
| Themenwelt | Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie |
| Naturwissenschaften ► Biologie | |
| Schlagworte | BK channels • Carbon Monoxide • gasotransmitter • Hydrogen sulfide • Nitric oxide • signaling molecules |
| ISBN-10 | 3-642-44652-3 / 3642446523 |
| ISBN-13 | 978-3-642-44652-8 / 9783642446528 |
| Zustand | Neuware |
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