The Retinal Müller Cell

Structure and Function

Vijay Sarthy, Harris Ripps (Autoren)

Buch | Softcover

278 Seiten

2014 | Softcover reprint of the original 1st ed. 2001
Springer-Verlag New York Inc.
978-1-4757-7456-6 (ISBN)

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The human brain contains more than a billion neurons which interconnect to form networks that process, store, and recall sensory information. These neuronal activities are supported by a group of accessory brain cells coll- tively known as neuroglia. Surprisingly, glial cells are ten times more - merous than neurons, and occupy more than half the brain volume (Hydén, 1961). Although long considered a passive, albeit necessary, component of the nervous system, many interesting and unusual functional properties of glial cells are only now being brought to light. As a result, the status of these cellular elements is approaching parity with nerve cells as a subject for experimental study. The term glia (or glue) seems today to be a misnomer in view of the diverse functions attributed to glial cells. Experimental studies in the last three decades have clearly established that the behavior of glial cells is far from passive, and that they are at least as complex as neurons with regard to their membrane properties. In addition, glial cells are of importance in signal processing, cellular metabolism, nervous system development, and the pathophysiology of neurological diseases. The Müller cell of the ver- brate retina provides a splendid example of an accessory cell that exhibits features illustrating every aspect of the complex behavior now associated with glial cells.

Structural Organization of Retinal Glia.- Role in Retinal Development.- Metabolic Interactions with Neurons.- Neuron-Glia Signaling Pathways.- K+ Dynamics, Ion Channels, and Transretinal Potentials.- Role in Retinal Pathophysiology.

Reihe/Serie	Perspectives in Vision Research
Zusatzinfo	1 Illustrations, color; 92 Illustrations, black and white; XIV, 278 p. 93 illus., 1 illus. in color.
Verlagsort	New York, NY
Sprache	englisch
Maße	152 x 229 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Humanbiologie
	Naturwissenschaften ► Biologie ► Zoologie
ISBN-10	1-4757-7456-7 / 1475774567
ISBN-13	978-1-4757-7456-6 / 9781475774566
Zustand	Neuware