Introduction to Evolutionary Genomics (eBook)

Naruya Saitou (Autor)

eBook Download: PDF

2014 | 2013. Auflage
XXIII, 461 Seiten
Springer London (Verlag)
978-1-4471-5304-7 (ISBN)

Infos

This book describes core processes of replication, mutation, neutral evolution and natural selection, genome evolution in prokaryotes, eukaryotes, vertebrates and humans, genome sequencing amd more, offering worked-out examples and extensive appendices.

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This book is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies. Features: introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection; presents a brief evolutionary history of life from the primordial seas to the emergence of humans; describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans; reviews methods for genome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building; discusses databases of genome sequences and related information, evolutionary distances, and population genomics; provides supplementary material at an associated website.

Autor

Dr. Naruya Saitou is a Professor in the Division of Population Genetics at the National Institute of Genetics, and a Professor in the Department of Genetics at the Graduate University for Advanced Studies, Mishima, Japan. He is also a Professor in the Department of Biological Sciences at the University of Tokyo, Japan.

Inhalt

Part I: Basic Processes of Genome Evolution
Basic Metabolism Surrounding DNAs
Mutation
Phylogeny
Neutral Evolution
Natural Selection
Part II: Evolving Genomes
Brief History of Life
Prokaryote Genomes
Eukaryote Genomes
Vertebrate Genomes
Human Genomes
Part III: Methods for Evolutionary Genomics
Genome Sequencing
Omic Data Collection
Databases
Sequence Homology Handling
Evolutionary Distances
Tree and Network Building
Population Genomics

Produkt-Details

• Sprache: englisch
• Themenwelt: Mathematik / Informatik ► Informatik
• Themenwelt: Naturwissenschaften ► Biologie ► Evolution
• Themenwelt: Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
• Schlagworte: Bioinformatics • Evolutionary Genomics • genomics • Molecular Evolution
• ISBN-10: 1-4471-5304-9 / 1447153049
• ISBN-13: 978-1-4471-5304-7 / 9781447153047