High-Performance Computational Solutions in Protein Bioinformatics

Dariusz Mrozek (Autor)

Buch | Softcover

XIX, 109 Seiten

2014 | 2014
Springer International Publishing (Verlag)
978-3-319-06970-8 (ISBN)

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Recent developments in computer science enable algorithms previously perceived as too time-consuming to now be efficiently used for applications in bioinformatics and life sciences. This work focuses on proteins and their structures, protein structure similarity searching at main representation levels and various techniques that can be used to accelerate similarity searches. Divided into four parts, the first part provides a formal model of 3D protein structures for functional genomics, comparative bioinformatics and molecular modeling. The second part focuses on the use of multithreading for efficient approximate searching on protein secondary structures. The third and fourth parts concentrate on finding 3D protein structure similarities with the support of GPUs and cloud computing. Parts three and four both describe the acceleration of different methods. The text will be of interest to researchers and software developers working in the field of structural bioinformatics and biomedical databases.

Formal Model of 3D Protein Structures for Functional Genomics, Comparative Bioinformatics, and Molecular Modeling.- Multithreaded PSS-SQL for Searching Databases of Secondary Structures.- GPU and CUDA for 3D Protein Structure Similarity Searching.- Cloud Computing for 3D Protein Structure Alignment.- General Discussion and Concluding Remarks.

Erscheint lt. Verlag	1.7.2014
Reihe/Serie	SpringerBriefs in Computer Science
Zusatzinfo	XIX, 109 p. 56 illus., 21 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	257 g
Themenwelt	Informatik ► Weitere Themen ► Bioinformatik
Themenwelt	Naturwissenschaften ► Biologie
Schlagworte	Amino Acid Sequence • Bioinformatics • Cloud Computing • GPU, CUDA • Multi-agent Systems • Multithreaded Processing • Parallel Processing • proteins • Protein Structure
ISBN-10	3-319-06970-5 / 3319069705
ISBN-13	978-3-319-06970-8 / 9783319069708
Zustand	Neuware