Cancer Therapy with Radiolabeled Antibodies
Crc Press Inc (Verlag)
978-0-8493-5112-9 (ISBN)
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Cancer Therapy with Radiolabeled Antibodies explores the most current experimental and clinical advances in the newly emerging field of cancer radioimmunotherapy (RAIT). Providing a multidisciplinary and international context, some of the world's leading experts examine the problems and prospects of RAIT from radiation, immunological, chemical, physical, physiological, and clinical perspectives with both overviews and original research.
Discussions cover the up-to-date clinical results in the RAIT of ovarian, breast, colorectal, and brain cancers, as well as the current status of RAIT in the management of B cell lymphomas. Radiobiology, dosimetry, radiochemistry, targeting biology in experimental models, clinical experiences in hematopoietic and solid tumors, and new approaches to improve cancer radioimmunotherapy are also discussed. In addition, new dosimetry concepts, new labeling methods, new concepts of antibody pharmacokinetics, and new methods to enhance selective cancer radioimmunotherapy are included.
Introduction, D.M. Goldenberg
Radiobiology, Radiation Physics, and Dosimetry
Medical Internal Dosimetry for High-Dose Radionuclide Therapies, D.R. Fisher
Radiolabeled Antibody Tumor Dosimetry, D.J. Buchsbaum and B.W. Wessels
Radiobiology and Radioimmunotherapy: Implications for Clinical Applications, J.R. Williams, R.R. Mayer, Y. Zhang, S.M. Quadri, and L.E. Dillehay
Radiochemistry of Therapeutic Radionuclides
Radiochemistry of Therapeutic Radionuclides, G.L. Griffiths
Advanced Methods for Rabiolabeling Monoclonal Antibodies with Therapeutic Radionuclides, O.A. Gansow and C. Wu
Antibody Radiolabeling with Isotopes of Rhenium, G.L. Griffiths
Targeting, Pharmacokinetics, and Experimental Radioimmunotherapy
Pharmacokinetics of Antibodies and Their Radiolabels, M.J. Mattes
Development of Cancer Radioimmunotherapy and Its Potential Use as an Adjuvant Treatment, R.M. Sharkey, R.D. Blumenthal, and D.M. Goldenberg
Experimental Radioimmunotherapy and Methods to Increase Therapeutic Efficacy, D.J. Buchsbaum
Clinical Radioimmunotherapy
Overview of Obstacles and Opportunities for Radioimmunotherapy of Cancer, G.L. DeNardo and S.J. DeNardo
Radioimmunotherapy of Ovarian Cancer, A. Maraveyas and A.A. Epenetos
Radioimmunotherapy of Colorectal Cancer, J.L. Murray
Radioimmunotherapy in the Treatment of Metastatic Breast Cancer: An Overview, S.J. DeNardo
Radioimmunotherapy of CNS Malignant Gliomas by Direct Intralesional Injection of Specific 131I Radiolabeled Monoclonal Antibodies, P. Riva, A. Arista, C. Sturiale, V. Tison, M. Frattarelli, S. Lazzari, G. Moscatelli, G. Franceschi, A. Spinelli, G. Sarti, M. Casi, N. Riva, and F. Campori
Treatment of B-Lymphocyte Malignancies with 131I-Lym-1 and 67Cu-2IT-BAT-Lym-1 and Opportunities for Improvement, G.L. DeNardo and S.J. DeNardo
Treatment of Relapsed B Cell Lymphomas with High-Dose Radioimmunotherapy and Bone Marrow Transplantation, O.W. Press, J.F. Eary, F.R. Appelbaum, and I.D. Bernstein
New Strategies
Clinical Application of the Avidin-Biotin System for Tumor Targeting, G. Paganelli, P. Magnani, A.G. Siccardi, and F. Fazio
Humanization of Monoclonal Antibodies: Molecular Approaches and Applications, A.S. Dion
Human Monoclonal Antibodies: Application in Radioimmunotherapy, J.L. Klein, R.L. DeJager, J.C.J. Stiekeme, M.V. Haspel, N.P. Pomato, R. Subramanian, and M.G. Hanna, Jr.
Cytokine-Based Modalities to Enhance Monoclonal-Antibody-Mediated Tumor Cell Killing, J.W. Greiner, S. Shimada, F. Guadagni, C.D. Ullmann, C. Nieroda, and J. Schlom
Overcoming Dose-Limiting, Antibody-Induced Myelotoxicity, R.D. Blumenthal, R.M. Sharkey, and D.M. Goldenberg
Index
| Erscheint lt. Verlag | 22.11.1994 |
|---|---|
| Zusatzinfo | 28 Halftones, black and white; 53 Tables, black and white |
| Verlagsort | Bosa Roca |
| Sprache | englisch |
| Maße | 178 x 254 mm |
| Gewicht | 816 g |
| Einbandart | gebunden |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren ► Nuklearmedizin | |
| Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren ► Radiologie | |
| Naturwissenschaften ► Chemie ► Physikalische Chemie | |
| ISBN-10 | 0-8493-5112-X / 084935112X |
| ISBN-13 | 978-0-8493-5112-9 / 9780849351129 |
| Zustand | Neuware |
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