Nucleic Acids in Immunology
Springer Berlin (Verlag)
978-3-642-87670-7 (ISBN)
Oligo- and Polynucleotides as Haptens (Part I).- Reading the Helix Backwards.- Methylated Bovine Serum Albumin as a Carrier for Oligo- and Poly-Nucleotides.- The Production of Antibodies to Mononucleotides, Oligonucleotides, and DNA.- Specific Antibodies to Polynucleotide Complexes and Their Reaction with Nucleic Acids: Importance of the Secondary Structure of the Antigen.- Specificity in the Reaction Between Anti-Pyrimidine Nucleoside Antibodies and DNA.- Antibodies to the Terminal Moieties of Guanine Mononucleotides and Guanine-Containing Dinucleotides.- Discussion.- Oligo- and Polynucleotides as Haptens (Part II).- Formation and Isolation of Antibodies Specific for Nucleotides.- The Reaction of Anti-Deoxyribonucleic Acid Sera with Nucleoside and Nucleotide Conjugates.- The Various Types of DNA Antibodies in Lupus Sera.- DNA and Nucleoprotein Determinants for Systemic Lupus Erythematosus Sera.- Cellular Phases of the Immune Response Following Immunization with Mammalian and Bacterial Ribosomes.- Discussion.- Use of Nucleic Acid-Specific Antibodies.- Immunological Evidence for the Existence of Thymine Dimers in Ultraviolet Irradiated DNA.- Immunological Evidence for the Identity of a Photoproduct Formed During Photooxidation of DNA with Methylene Blue, Rose Bengal, Thionin and Acridine Orange.- Use of Anti-RNA Antibodies in the Study of the Structure of Polynucleotides and Ribosomal Particles.- Inhibition of Bacterial Transformation by Nucleic Acid-Specific Antibodies.- Effects of Anti-Hapten Antibodies on the Biological Activities of Nucleic Acids.- Use of Fluorescein-Labelled Anti-Nuclear Antibodies in the Study of Chromosomal Structure.- Discussion.- Role of the Carrier in the Production of Hapten-Specific Antibodies.- The Genetic Control of the Immune Response to Hapten-Poly-L-Lysine Conjugates in Guinea Pigs.- The Relationship of the Hapten to the Carrier in the Induction and Specificity of the Immune Response.- Importance of Immunogenicity of the Carrier in Inducing a Response Against Carrier-Synthetic Polymer Aggregates.- Specificity of the Immune Response as a Function of the Carrier.- The Role of Conformation in the Structure of Antigenic Sites.- Discussion.- Nucleic Acids as Non-Specific Stimulators of Immune Responses.- Stimulation of Antibody-Forming Cells by Oligonucleotides of Known Composition.- Influence of Oligonucleotides of Known Composition on Rates of DNA Synthesis in Pneumococci.- Enhancement of Antibody Formation by Nucleic Acids and Their Derivatives.- Restoration of Immunologic Capacities in Irradiated Animals by Nucleic Acids and Their Derivatives.- Nucleic Acids and Induction of Antibody Synthesis in Inhibited Systems.- Induction of an Allogeneic-like Inhibition by Means of DNA Obtained from Untreated Cells.- Discussion.- Role of Nucleic Acids in Specific Antibody Formation (Part I).- Antibody Formation Initiated in vitro with RNA and RNA-Antigen Complexes.- Roles of DNA and RNA in the Antibody Response.- The Antigen-RNA Complex of Macrophages.- On the Role of Antigen Fragments and RNA in the Immune Response of Rabbits to a Soluble Antigen.- The Nature of Immunogenic RNA-Antigen Complexes in Immune and Tolerant Mice.- Stimulation of Anti-Tumor Activity of the Host with RNA from Immune Lymphocytes.- Discussion.- Role of Nucleic Acids in Specific Antibody Formation (Part II).- Fractionation of RNA Capable of Transferring Transplantation Immunity.- Induction of Accelerated Graft Rejection and Enhanced Graft-Versus-Host Reaction with RNA from Lymphoid Organs of Animals Immunized with Allogeneic Tissues.- UniqueSpecies of RNA in Peritoneal Cells Exposed to Different Antigens.- Studies in vitro on Immunoglobulin Biosynthesis.- Synthesis and Assembly of Immunoglobulin.- On the Role of Nucleic Acids as Genes Conferring Precise Chemospecificity to Differentiated Cell Lines.- Studies on the Multiple Isoaccepting Transfer Ribonucleic Acids in Mouse Plasma Cell Tumors.- Isolation and Characterization of RNA Produced in Response to Antigen.- Discussion.- Text of Speech Presented at the Symposium Banquet.- The Molecular Biology of Expectation.
Erscheint lt. Verlag | 20.11.2013 |
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Zusatzinfo | XVII, 724 p. |
Verlagsort | Berlin |
Sprache | englisch |
Maße | 155 x 235 mm |
Gewicht | 1031 g |
Themenwelt | Studium ► Querschnittsbereiche ► Infektiologie / Immunologie |
Naturwissenschaften ► Biologie | |
Schlagworte | Antigen • biochemistry • biomedical research • Chemistry • Diseases • immune response • immunology • Protein |
ISBN-10 | 3-642-87670-6 / 3642876706 |
ISBN-13 | 978-3-642-87670-7 / 9783642876707 |
Zustand | Neuware |
Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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