Oncogene and Transgenics Correlates of Cancer Risk Assessments
Springer-Verlag New York Inc.
978-1-4613-6333-0 (ISBN)
Cancer Risk Assessments: An Overview.- Pharmacodynamic Models for Cancer Risk Assessment.- Predictive Value for Cancer Risk Assessment of Cell-and Tissue-Specific Formation of Carcinogen-DNA Adducts.- Studies on the Role of Protein Kinase C in Multistage Carcinogenesis and Their Relevance to Risk Extrapolation.- Oncogene Activation and Human Cancer.- Genetics of Hepatocarcinogenesis in Mouse and Man.- Protein Kinase C in Carcinogenesis: Comparative Expression of Oncogenes and Protein Kinase C in Rhabdomyosarcoma Models.- Oncogenes and Human Cancers.- ‘In Vivo’ Model Systems to Study ras Oncogene Involvement in Carcinogenesis.- K-ras Oncogene Activation in Neoplasias of Patients with Familial Adenomatous Polyposis or Kidney Transplant.- An Overview of Transgenic Mice as Future Models of Human Diseases, In Drug Development, And for Genotoxicity and Carcinogenesis Studies.- Regulating Gene Expression in Mammalian Cell Culture and Transgenic Mice with Yeast Gal4/Uas Control Elements.- Genes and Oncogenes of the ras Superfamily.- Oncogenic Transgenic Mice in the Study of Carcinogenesis.- Leukemia, Lymphoma, Embryonic Carcinoma and Hepatoma Induced in Transgenic Rabbits by the c-myc Oncogene Fused with Immunoglobulin Enhancers.- An Overview of the Outstanding Issues in the Risk Assessment of Methylene Chloride.- Cancer Dose-Response Modeling and Methylene Chloride.- Risk Assessments for Benzene-Induced Leukemia — A Review.- Comparative Metabolism and Genotoxicity Data on Benzene: Their Role in Cancer Risk Assessment.- Dose-Response Relationships for Benzene: Human and Experimental Carcinogenicity Data.- A Threshold for Benzene Leukemogenesis.- Some Points for Discussion from the Oncogene Workshop.- Concluding Remarks, Findings and Recommendations.
Reihe/Serie | Nato Science Series: A ; 232 |
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Zusatzinfo | XI, 351 p. |
Verlagsort | New York, NY |
Sprache | englisch |
Maße | 156 x 244 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Naturwissenschaften ► Biologie ► Biochemie | |
Naturwissenschaften ► Biologie ► Botanik | |
Naturwissenschaften ► Biologie ► Zoologie | |
ISBN-10 | 1-4613-6333-0 / 1461363330 |
ISBN-13 | 978-1-4613-6333-0 / 9781461363330 |
Zustand | Neuware |
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