Biophysics and Cancer
Springer-Verlag New York Inc.
978-1-4612-9258-6 (ISBN)
1. Normal Cells and Cancer Cells: Macromolecular Structures and Cellular Functions.- 1.1. Background.- 1.2. Native Chromatin-DNA Structure.- 1.3. Nuclear Structure.- 1.4. What Is a Gene?.- 1.5. Ribosomes.- 1.6. Modification in the Control of Cell Proliferation.- 1.7. Modifications in the Control of Cell Differentiation.- 1.8. Modifications in the Control of Cell Transformation.- 1.9. Modifications in the Control of Cellular Aging.- 1.10. Membranes.- 1.11. Cytoskeleton.- 1.12. Control Mechanisms for Normal versus Abnormal Cell Growth.- 1.13. Molecular Mechanisms and Models for Gene Expression.- 1.14. Conclusions and Future Trends.- 2. Cancer Cause and Prevention.- 2.1. Background.- 2.2. Possible Causes of Cancer.- 2.3. Cancer Prevention.- 3. Cancer Detection and Treatment.- 3.1. Background.- 3.2. Present Status of Human Cancer Detection and Treatment.- 3.3. Alternative Analytical Approaches.- 3.4. New Observables.- 3.5. Theoretical Simulation at the Cellular Level: Optimized Drug Metabolism Parameters in Animals.- 3.6. Treatment Optimization in Animals.- 3.7. Drug Interaction and Molecular Perturbation in Animals.- 3.8. Extrapolation to Human Cancer.- 4. Experimental Probes.- 4.1. Background.- 4.2. Preparative Tools.- 4.3. Probes for Lower-Order Structures.- 4.4. Probes for Higher-Order Structures in Situ.- 5. Theoretical Probes.- 5.1. Background.- 5.2. Enzyme Kinetics.- 5.3. Signal Processing and Analysis.- 5.4. Statistical Mechanics and Thermodynamics of Cell Structures.- 5.5. Polyelectrolyte Theory of Interactions among Biopolymers.- 5.6. Physicochemical Model for Dye-Nucleic Acid Interaction in Situ.- 5.7. Electromagnetic Theory of Polarized Light Scattering by Large Biopolymers.- 5.8. Random Walk Model of Biopolymers.- 5.9. Mean Field Theory of Gel Biopolymers.- Epilogue: A Final Comment.- Problems.- References.
Zusatzinfo | 480 p. |
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Verlagsort | New York, NY |
Sprache | englisch |
Maße | 152 x 229 mm |
Themenwelt | Sachbuch/Ratgeber ► Natur / Technik ► Garten |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
Naturwissenschaften ► Biologie ► Zoologie | |
Naturwissenschaften ► Physik / Astronomie ► Angewandte Physik | |
ISBN-10 | 1-4612-9258-1 / 1461292581 |
ISBN-13 | 978-1-4612-9258-6 / 9781461292586 |
Zustand | Neuware |
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