Molecular Biology and Evolution of Blood Group and MHC Antigens in Primates

Antoine Blancher, Jan Klein, Wladyslaw W. Socha (Herausgeber)

Buch | Softcover

XIV, 570 Seiten

2013 | 1. Softcover reprint of the original 1st ed. 1997
Springer Berlin (Verlag)
978-3-642-63843-5 (ISBN)

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Zoologists have categorized primates into a single order, and no one doubts today that they share a common ancestry. Humans and Old and New World non human primate species, from the lemurs of Madagascar to the African anthro poid apes, represent diverging branches of an evolutionary common trunk. Along with species-specific characters, all primates have retained a number of ancestral traits, relics of their common origin. The comparative study of these species-specific and ancestral traits makes it possible to reconstruct the evolu tionary pathways of humans and nonhuman primates. The discovery of the human blood groups and, later, of the Major Histocom patibility Complex (MHC) had a seminal effect on the field of human genetics, providing the first sound examples of mendel ian polymorphisms. The use of blood group and MHC alleles as genetic markers in biological anthropology gen erated a conceptual revolution and persuaded researchers to begin to think in terms of populations and not only intems of typology. The counterparts of these human red and white cell antigens were found and studied in nunhuman primates, and progress in this field is summarized in this book.

Contents: Taxonomy and Phylogeny of Primates.- Red Blood Cell Antigens.- Major Histocompatibility Complex.

"The extensive list of references, MHC nucleotide sequences of nonhuman primates, and numerous tables and figures make this a valuable handbook for experts in the field of nonhuman primates. It also provides a comprehensive review of human blood and MHC antigens for clinicians in the fields of hematology, transplantation and transfusion medicine." International Journal of Hematology

Erscheint lt. Verlag	21.1.2013
Zusatzinfo	XIV, 570 p. 117 illus., 1 illus. in color.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	878 g
Themenwelt	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
Themenwelt	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
Schlagworte	Allele • Antibody • Antigen • Antigene • Biology • Blood • blood groups antigens • Blutgruppen • Evolutin • genes • Genetics • Haupthistokompatibilitätskomplex • Histocompatibility • immune response • major histocompatibility complex • Molecular Biology • Molekularbiologie • Nonhuman Primates • Phylogeny • Primaten • Primates • Vaccine
ISBN-10	3-642-63843-0 / 3642638430
ISBN-13	978-3-642-63843-5 / 9783642638435
Zustand	Neuware