Gene Function Analysis
Humana Press Inc. (Verlag)
978-1-62703-720-4 (ISBN)
Authoritative and easily accessible, Gene Function Analysis, Second Edition seeks to serve both professionals and novices with a growing understanding of the complexity of gene function.
The Present State and Future Direction of Integrated Gene Function Analysis.- Performing Integrative Functional Genomics Analysis in GeneWeaver.org.- Functional Annotation of Differentially Regulated Geneset Using WebGestalt: A Geneset Predictive of Response to Ipilimumab in Tumor Biopsies.- Integrative Data-Mining Tools to Link Fene and Function.- Detection of Driver Protein Complexes in Breast Cancer Metastasis by Large Scale Transcriptome-Interactome Integration.- Pattern Identification in Time Course Gene Expression Data with the CoGAPS Matrix Factorization.- Statistical Tools and R Software for Cancer Driver Probabilities.- Predicting the Functional Consequences of Somatic Missense Mutations Found in Tumors.- Determining the Effect of DNA Methylation on Gene Expression in Cancer Cells.- Reverse Engineering Transcriptional Gene Network.- Integrating In Silico Resources to Map a Signaling Network.- A Method for Inducible Gene Over-Expression and Down-Regulation in Emerging Model Species Using Pogostick.- Construction and Application of Site-specific Artificial Nucleases for Targeted Gene Editing.- Selection of Recombinant Antibodies from Antibody Gene Libraries.- Construction of Simple and Efficient siRNA Validation Systems for Screening and Identification of Effective RNAi-Targeted Sequences from Mammalian Genes.- Rapid Genetic Modification of Mouse Embryonic Stem Cells by Inducible Cassette Exchange Recombination.- In Ovo Electroporation of miRNA-Based Plasmids to Investigate Gene Functionin the Developing Neural Tube.- Proteomic Strategies: SILAC and 2D-DIGE - Powerful Tool to Investigate Cellular Alterations.- Conditional Gene-Trap Mutagenesis in Zebrafish.
Erscheint lt. Verlag | 14.11.2013 |
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Reihe/Serie | Methods in Molecular Biology ; 1101 |
Zusatzinfo | 86 Illustrations, color; 37 Illustrations, black and white; XIII, 416 p. 123 illus., 86 illus. in color. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
Schlagworte | functional genomic analysis • gene expression • Gene function • signaling network • transcription gene network |
ISBN-10 | 1-62703-720-9 / 1627037209 |
ISBN-13 | 978-1-62703-720-4 / 9781627037204 |
Zustand | Neuware |
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