African Horse Sickness
Springer Wien (Verlag)
978-3-211-83132-8 (ISBN)
Epidemiology.- Taxonomy of African horse sickness viruses.- Epidemiology of African horse sickness and the role of the zebra in South Africa.- Transmission and distribution of African horse sickness virus serotypes in South African zebra.- Serological and virological responses in mules and donkeys following inoculation with African horse sickness virus serotype 4.- Donkeys as reservoirs of African horse sickness virus.- Clinical, virological and immune responses of normal and immunosuppressed donkeys (Equus asinus africanus) after inoculation with African horse sickness virus.- Immunohistochemical demonstration of African horse sickness viral antigen in tissues of experimentally infected equines.- Entomology.- The 1996 outbreak of African horse sickness in South Africa - the entomological perspective.- The seasonal and geographical distribution of Culicoides imicola, C. pulicaris group and C. obsoletus group biting midges in central and southern Spain.- The relationship between climate and the distribution of Culicoides imicola in Iberia.- Simulation studies of African horse sickness in Spain.- The Culicoides vectors of African horse sickness virus in Morocco: distribution and epidemiological implications.- Studies of the mortality rate of Culicoides imicola in Morocco.- Modelling the distribution and abundance of Culicoides imicola in Morocco and Iberia using climatic data and satellite imagery.- Effect of temperature on African horse sickness virus infection in Culicoides.- Duration of repellency of various synthetic and plant-derived preparations for Culicoides imicola, the vector of African horse sickness virus.- Molecular biology.- New generation of African horse sickness virus vaccines based on structural and molecular studies of the virus particles.- Expressionof the major core structural proteins VP3 and VP7 of African horse sickness virus, and production of core-like particles.- VP7 from African horse sickness virus serotype 9 protects mice against a lethal, heterologous serotype challenge.- Molecular epidemiology of African horse sickness virus based on analyses and comparisons of genome segments 7 and 10.- Structural studies of orbivirus particles.- Characterization of two African horse sickness virus nonstructural proteins, NS1 and NS3.- Development of a mouse model system, coding assignments and identification of the genome segments controlling virulence of African horse sickness virus serotypes 3 and 8.- Phylogenetic analysis of African horse sickness virus segment 10: sequence variation, virulence characteristics and cell exit.- Vaccines and diagnosis.- Future international management of African horse sickness vaccines.- Application of an indirect fluorescent antibody assay for the detection of African horse sickness virus antibodies.- Validation of ELISA for the detection of African horse sickness virus antigens and antibodies.- Use of reverse transcriptase-polymerase chain reaction (RT-PCR) and dot-blot hybridisation for the detection and identification of African horse sickness virus nucleic acids.- Western immunoblotting as a method for the detection of African horse sickness virus protein-specific antibodies: Differentiation between infected and vaccinated horses.- Conclusions and recommendations of the meeting.
Erscheint lt. Verlag | 16.9.1998 |
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Reihe/Serie | Archives of Virology. Supplementa |
Zusatzinfo | VIII, 344 p. 105 illus., 9 illus. in color. |
Verlagsort | Vienna |
Sprache | englisch |
Maße | 210 x 279 mm |
Gewicht | 964 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin |
Medizin / Pharmazie ► Studium | |
Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
Naturwissenschaften ► Biologie ► Zoologie | |
Schlagworte | Afrikanische Pferdekrankheit • Arbovirology • Diagnosis • epidemiology • Equines • HC/Medizin/Klinische Fächer • HC/Medizin/Nichtklinische Fächer • Polymer • Protein • RNA • Veterinary Science • Virus |
ISBN-10 | 3-211-83132-0 / 3211831320 |
ISBN-13 | 978-3-211-83132-8 / 9783211831328 |
Zustand | Neuware |
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