Human Cytogenetics: Malignancy and Acquired Abnormalities
A Practical Approach
Seiten
2001
|
3rd Revised edition
Oxford University Press (Verlag)
978-0-19-963842-0 (ISBN)
Oxford University Press (Verlag)
978-0-19-963842-0 (ISBN)
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Cytogenetics is concerned with matching inherited traits with the appearance, structure, and behaviour of chromosomes. Human Cytogenetics: Malignant and Acquired Abnormalities describes the techniques used to study how chromosomal rearrangements can cause malignancies. The basic techniques of human cytogenetics are covered in a separate volume.
The advent of molecular technologies has lead to a rapid acceleration in the cytogenetic study of malignancy and acquired abnormalities. As well as having a chapter devoted to molecular technologies (FISH, PRINS, and CGH), molecular methodology is emphasized in all chapters, for example the role of CGH in solid tumour cytogenetics. Classical techniques are not forgotten, with a detailed description of the preparation and analysis of chromosomes from bone marrow and
leukaemic blood. This is followed by three chapters on the specific methodology for the cytogenetic study of myeloid leukaemia, acute lymphoblastic leukaemia, and lymphomas and lymphoproliferative disorders. Also covered are chromosome instability syndromes, mutagen-induced chromosome damage in
lymphocytes and the role of cytogenetics in the assessment of haematological disorders. This book will be invaluable to any scientists using cytogenetics to study malignancy and along with its sister volume Human Cytogenetics: Constitutional Analysis will be an essential purchase for any cytogenetics laboratory. The volumes are available individually or as a set.
The advent of molecular technologies has lead to a rapid acceleration in the cytogenetic study of malignancy and acquired abnormalities. As well as having a chapter devoted to molecular technologies (FISH, PRINS, and CGH), molecular methodology is emphasized in all chapters, for example the role of CGH in solid tumour cytogenetics. Classical techniques are not forgotten, with a detailed description of the preparation and analysis of chromosomes from bone marrow and
leukaemic blood. This is followed by three chapters on the specific methodology for the cytogenetic study of myeloid leukaemia, acute lymphoblastic leukaemia, and lymphomas and lymphoproliferative disorders. Also covered are chromosome instability syndromes, mutagen-induced chromosome damage in
lymphocytes and the role of cytogenetics in the assessment of haematological disorders. This book will be invaluable to any scientists using cytogenetics to study malignancy and along with its sister volume Human Cytogenetics: Constitutional Analysis will be an essential purchase for any cytogenetics laboratory. The volumes are available individually or as a set.
| Erscheint lt. Verlag | 28.6.2001 |
|---|---|
| Reihe/Serie | Practical Approach Series ; 241 |
| Zusatzinfo | 8 plates, numerous halftones and line figures |
| Verlagsort | Oxford |
| Sprache | englisch |
| Maße | 194 x 253 mm |
| Gewicht | 863 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Laboratoriumsmedizin |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Histologie / Embryologie | |
| Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| ISBN-10 | 0-19-963842-X / 019963842X |
| ISBN-13 | 978-0-19-963842-0 / 9780199638420 |
| Zustand | Neuware |
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