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Computational and Statistical Methods for Protein Quantification by Mass Spectrometry (eBook)

eBook Download: EPUB
2012
John Wiley & Sons (Verlag)
9781118493779 (ISBN)

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Computational and Statistical Methods for Protein Quantification by Mass Spectrometry - Ingvar Eidhammer, Harald Barsnes, Geir Egil Eide, Lennart Martens
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The definitive introduction to data analysis in quantitative proteomics

This book provides all the necessary knowledge about mass spectrometry based proteomics methods and computational and statistical approaches to pursue the planning, design and analysis of quantitative proteomics experiments. The author’s carefully constructed approach allows readers to easily make the transition into the field of quantitative proteomics. Through detailed descriptions of wet-lab methods, computational approaches and statistical tools, this book covers the full scope of a quantitative experiment, allowing readers to acquire new knowledge as well as acting as a useful reference work for more advanced readers.

Computational and Statistical Methods for Protein Quantification by Mass Spectrometry:

  • Introduces the use of mass spectrometry in protein quantification and how the bioinformatics challenges in this field can be solved using statistical methods and various software programs.
  • Is illustrated by a large number of figures and examples as well as numerous exercises.
  • Provides both clear and rigorous descriptions of methods and approaches.
  • Is thoroughly indexed and cross-referenced, combining the strengths of a text book with the utility of a reference work.
  • Features detailed discussions of both wet-lab approaches and statistical and computational methods.

With clear and thorough descriptions of the various methods and approaches, this book is accessible to biologists, informaticians, and statisticians alike and is aimed at readers across the academic spectrum, from advanced undergraduate students to post doctorates entering the field.


The definitive introduction to data analysis in quantitative proteomics This book provides all the necessary knowledge about mass spectrometry based proteomics methods and computational and statistical approaches to pursue the planning, design and analysis of quantitative proteomics experiments. The author s carefully constructed approach allows readers to easily make the transition into the field of quantitative proteomics. Through detailed descriptions of wet-lab methods, computational approaches and statistical tools, this book covers the full scope of a quantitative experiment, allowing readers to acquire new knowledge as well as acting as a useful reference work for more advanced readers. Computational and Statistical Methods for Protein Quantification by Mass Spectrometry: Introduces the use of mass spectrometry in protein quantification and how the bioinformatics challenges in this field can be solved using statistical methods and various software programs. Is illustrated by a large number of figures and examples as well as numerous exercises. Provides both clear and rigorous descriptions of methods and approaches. Is thoroughly indexed and cross-referenced, combining the strengths of a text book with the utility of a reference work. Features detailed discussions of both wet-lab approaches and statistical and computational methods. With clear and thorough descriptions of the various methods and approaches, this book is accessible to biologists, informaticians, and statisticians alike and is aimed at readers across the academic spectrum, from advanced undergraduate students to post doctorates entering the field.

Ingvar Eidhammer, Department of Informatics, University of Bergen, Norway Harald Barsnes, Department of Biomedicine, University of Bergen, Norway Geir Egil Eide, Centre for Clinical Research, Haukeland University,Norway Lennart Martens, Department of Biochemistry, Faculty of Medicine and Health Sciences, Ghent University, Belgium

"Computational and Statistical Methods for Protein
Quantification by Mass Spectrometry is a book that can be used by
undergraduate students in both analytical chemistry and
biochemistry, as well as by scientists who are familiar with the
field. The book teaches the reader how to perform proteomic
analysis by mass spectrometry and how to interpret the large amount
of data collected." (Analytical and Bioanalytical
Chemistry, 10 January 2014)

Erscheint lt. Verlag 10.12.2012
Sprache englisch
Themenwelt Mathematik / Informatik Mathematik Statistik
Mathematik / Informatik Mathematik Wahrscheinlichkeit / Kombinatorik
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Chemie Analytische Chemie
Technik
Schlagworte Biowissenschaften • Chemie • Chemistry • Computational & Graphical Statistics • Computational and Statistical Methods for Protein Quantification by Mass Spectrometry, Quantitative Proteomics, Correlations of mRNA and Protein Abundances, Protein Level Quantification, Protein Identification, MS/MS Quantification, Biomarkers • Genomforschung u. Proteomik • Genomics & Proteomics • Life Sciences • Massenspektrometrie • Mass Spectrometry • Rechnergestützte u. graphische Statistik • Rechnergestützte u. graphische Statistik • Statistics • Statistik
ISBN-13 9781118493779 / 9781118493779
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