The Myc Gene
Humana Press Inc. (Verlag)
978-1-62703-428-9 (ISBN)
The Myc world within Reach.- Methods for the Expression, Purification, Preparation and Biophysical Characterization of Constructs of the c-Myc and Max b-HLH-LZs.- Analyzing Myc in Cell Transformation and Evolution.- Identifying Myc Interactors.- Detection of c-Myc Protein-Protein Interactions And Phosphorylation Status by Immunoprecipitation.- An Efficient Way of Studying Protein–Protein Interactions Involving HIF-α, c-Myc, and Sp1.- Methods for Determining Myc-induced Apoptosis.- Methods to Study Myc-regulated Cellular Senescence.- Chromatin Immunoprecipitation Assays for Myc and N-Myc.- Methods to Quantify microRNAs in the Myc Gene Network for Posttranscriptional Gene Repression.- Genome-wide Analysis of c-MYC-regulated mRNAs and miRNAs, and c-MYC DNA-binding by Next Generation Sequencing.- A High Throughput siRNA Screening Platform to Identify MYC Synthetic Lethal Genes as Candidate Therapeutic Targets.- Investigating Myc-dependent Translational Regulation in Normal and Cancer Cells.- Studying Myc’s Role in Metabolism Regulation.- Generation of a Tetracycline Regulated Mouse Model of MYC-induced T-cell Acute Lymphoblastic Leukemia.- Methods to Assess Myc Function in Intestinal Homeostasis, Regeneration and Tumourigenesis.- Detection of c-myc Amplification in Formalin-fixed Paraffin-Embedded Tumor Tissue by Chromogenic in situ Hybridization (CIHS).- Cell-Based Methods for the Identification of MYC-Inhibitory Small Molecules.
Erscheint lt. Verlag | 5.9.2013 |
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Reihe/Serie | Methods in Molecular Biology ; 1012 |
Zusatzinfo | 29 Illustrations, color; 15 Illustrations, black and white; XI, 282 p. 44 illus., 29 illus. in color. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
Naturwissenschaften ► Biologie ► Zellbiologie | |
Schlagworte | Cancer • Cancer Therapy • Cellular functions • In vitro and in vivo • Myc • Myc mechanism |
ISBN-10 | 1-62703-428-5 / 1627034285 |
ISBN-13 | 978-1-62703-428-9 / 9781627034289 |
Zustand | Neuware |
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