Trinucleotide Repeat Protocols
Humana Press Inc. (Verlag)
978-1-62703-410-4 (ISBN)
Authoritative and easily accessible, Trinucleotide Repeat Protocols, Second Edition seeks to serve researchers with its thorough methodologies on this expanding field.
A Brief History of Triplet Repeat Disease.- Huntington's Disease and Cell Therapies: Past, Present and Future.- Transcranial Two-Photon Imaging of Synaptic Structures in the Cortex of Awake Head-Restrained Mice.- In vivo Imaging of Synapse Plasticity in the Mouse Motor Cortex.- Pluripotent Hybrid Stem Cells from Transgenic Huntington’s Disease Monkey.- Mesenchymal Stem Cells for Trinucleotide Repeat Disorders.- Lentiviral-Mediated Gene Transfer of siRNAs for the Treatment of Huntington's Disease.- Purification of dFMR1-Containing Complexes Using Tandem Affinity Purification.- Combined FISH and Immunofluorescent Staining Methods to Co-localize Proteins and mRNA in Neurons and Brain Tissue.- Epigenetic Modifications of the FMR1 Gene.- The CGG Repeat and the FMR1 Gene.- Study of Oxidative Damage and Antioxidant Systems in Two Huntington´s Disease Rodent Models.- Regulation of Ataxin-1 Phosphorylation and Its Impact on Biology.- Towards Understanding Region-Specificity of Triplet Repeat Diseases: Coupled Immunohistology and Mass Spectrometry Imaging.- Antibodies and Intrabodies Against Huntingtin: Production and Screening of Monoclonals and Single-Chain Recombinant Forms.- Cell Recovery from DM1 Transgenic Mouse Tissue to Study (CTG)n Instability and DM1 Pathogenesis.- Markerless Modification of Trinucleotide Repeat Loci in BACs.- DRPLA: Recent Advances in Research Using Transgenic Mouse Models.
Reihe/Serie | Methods in Molecular Biology ; 1010 |
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Zusatzinfo | 24 Illustrations, color; 40 Illustrations, black and white; XIII, 296 p. 64 illus., 24 illus. in color. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
Schlagworte | DNA Modification • ES cells • Protein modification • RNA • synaptic plasticity • trinucleotide repeat disease |
ISBN-10 | 1-62703-410-2 / 1627034102 |
ISBN-13 | 978-1-62703-410-4 / 9781627034104 |
Zustand | Neuware |
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