Cancer as a Metabolic Disease (eBook)
448 Seiten
John Wiley & Sons (Verlag)
978-1-118-31030-4 (ISBN)
and provides solutions to cancer management and prevention. It
expands upon Otto Warburg's well-known theory that all cancer is a
disease of energy metabolism. However, Warburg did not link
his theory to the "hallmarks of cancer" and thus his theory was
discredited. This book aims to provide evidence, through
case studies, that cancer is primarily a metabolic disease
requring metabolic solutions for its management and
prevention. Support for this position is derived from
critical assessment of current cancer theories. Brain cancer
case studies are presented as a proof of principle for metabolic
solutions to disease management, but similarities are drawn to
other types of cancer, including breast and colon, due to
the same cellular mutations that they demonstrate.
THOMAS N. SEYFRIED, PhD, has taught and conducted research in the fields of neurogenetics, neurochemistry, and cancer for more than twenty-five years at Yale University and Boston College. He has published more than 150 scientific articles and book chapters and is on the editorial boards of Nutrition & Metabolism, Journal of Lipid Research, Neurochemical Research, and ASN Neuro.
Chapter 1. Images of Cancer
Chapter 2. Confusion surrounds the origin of cancer
Chapter 3. Cancer Models
Chapter 4. Energetics of normal cells and cancer cells
Chapter 5. Respiratory Dysfunction in Cancer Cells
Chapter 6. The Warburg Dispute
Chapter 7. Is Respiration Normal in Most Cancer Cells?
Chapter 8. Is Mitochondrial Glutamine Fermentation the Missing Link in the Metabolic Theory of Cancer?
Chapter 9. Genes, Respiration, Viruses, Cancer
Chapter 10. Respiratory Injury, the retrograde response, and the origin of cancer
Chapter 11. Mitochondria: The ultimate tumor suppressor
Chapter 12. Linking Abnormalities in Growth Control, Telomerase Activity
Chapter 13. Metastasis
Chapter 14. Mitochrondrial Respiratory Dysfunction and the Extrachromosomal Origin of Cancer
Chapter 15. Nothing in Cancer Biology Makes Sense Except in the Light of Evolution
Chapter 16. Cancer Treatment Strategies
Chapter 17. Metabolic management of cancer
Chapter 18. Implementation of Metabolic Therapies for Cancer Management
Chapter 19. Cancer Prevention
Chapter 20. Case Studies and Personal Experiences in Using the Ketogenic Diet for Cancer Management
Chapter 21. Conclusions
"This book offers a refreshing perspective for anyone
wanting to get a comprehensive background on the newer emerging
interest in targeting cancer metabolism for therapy."
(Doody's, 11 January 2013)
"For the first time, an entire issue is being devoted to a
review article based on a recent medical book. This is a departure
from our usual format, but I think you will agree that this topic
warrants the detailed treatment we have given it . . .This book
should be required reading for all scientifically literate people
who are involved in the cancer problem." (Advances
in Cancer Treatment, 1 October 2012)
| Erscheint lt. Verlag | 18.5.2012 |
|---|---|
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Allgemeines / Lexika |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
| Naturwissenschaften ► Biologie | |
| Technik | |
| Schlagworte | Biochemie u. Chemische Biologie • Biochemistry (Chemical Biology) • Biowissenschaften • Chemie • Chemische Biologie • Chemistry • Life Sciences • Medical oncology • Medical Science • Medizin • medizinische Onkologie • Neuroscience • Neurowissenschaften • Onkologie |
| ISBN-10 | 1-118-31030-6 / 1118310306 |
| ISBN-13 | 978-1-118-31030-4 / 9781118310304 |
| Haben Sie eine Frage zum Produkt? |
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