Pathogenicity Islands and the Evolution of Pathogenic Microbes

Volume I

J. Hacker, J.B. Kaper (Herausgeber)

Media-Kombination

XXXIV, 444 Seiten | Ausstattung: Softcover

2012 | 1. Softcover reprint of the original 1st ed. 2002
Springer Berlin
978-3-642-62720-0 (ISBN)

Infos

It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements.

Inhalt

List of Contents.- Evolution of Prokaryotic Genomes.- Extraintestinal Escherichia coli as a Model System for the Study of Pathogenicity Islands.- Pathogenicity Islands of Intestinal E. coli.- Pathogenicity Islands of Shigella.- Pathogenicity Islands and Host Adaptation of Salmonella Serovars.- Plasmids and Pathogenicity Islands of Yersinia.- Genomic Organization of LPS-Specific Loci.- Genomic Structure of Capsular Determinants.- Genome Plasticity in Pathogenic and Nonpathogenic Enterobacteria.- Phylogenetic Relationships and Virulence Evolution in the Genus Bordetella.- Pathogenicity Islands and PAI-Like Structures in Pseudomonas Species.

Rezensionen

From the reviews:

"This compendium brought together by J. Hacker and J. B. Kaper as editors, features an international assembly of authors ... giving a lucid introduction into the evolution of prokaryotic genomes. The ... work provides a comprehensive overview of the current state of knowledge on PAIs and other mobile virulence determinants in bacterial as well as fungal pathogens of humans and plants." (Susanne Rohrer, BioWorld, Issue 61, 2002)

Produkt-Details

• Erscheint lt. Verlag: 6.10.2012
• Reihe/Serie: Current Topics in Microbiology and Immunology
• Zusatzinfo: XXXIV, 444 p. In 2 volumes, not available separately.
• Verlagsort: Berlin
• Sprache: englisch
• Maße: 155 x 235 mm
• Gewicht: 391 g
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
• Themenwelt: Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
• Schlagworte: Bacillus cereus • Bacteria • Dichelobacter nodosus • DNA • Escherichia coli • Fungi • Gene • genes • gene transfer • genome structure • Helicobacter pylori • Helicobacter pylori / Campylobacter pylori • Legionella • Listeria • microbe • microbes • Neisseria • pathogenesis • pathogenic fungi • Pseudomonas • resistance • yersinia
• ISBN-10: 3-642-62720-X / 364262720X
• ISBN-13: 978-3-642-62720-0 / 9783642627200
• Zustand: Neuware