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Molecular and Translational Vascular Medicine (eBook)

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2012 | 2012
XIV, 338 Seiten
Humana Press (Verlag)
978-1-61779-906-8 (ISBN)

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Molecular and Translational Vascular Medicine will serve as a state-of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of vascular medicine.  The text provides new insight into the basic mechanisms of classic vascular pathophysiologic processes like angiogenesis, atherosclerosis, thrombosis, and vasculitis.  Furthermore, it covers new areas of investigation including the role of the ubiquitin proteasome system in vascular disease, endothelial progenitor cells for disease treatment, and the genetic basis of thoracic aortic aneurysms.  Lastly, this volume includes sections on the newly emerging field of therapeutic angiogenesis, and the developing technology of nanoparticle-based imaging and therapeutic treatment of the diseased vasculature. All chapters are written by established experts in their fields, including pathologists, cardiovascular surgeons, and internists as well as translational biomedical researchers in a wide range of disciplines. While comprehensive, the material is presented in a manner that simplifies the complex pathophysiologic mechanisms that underlie common vascular diseases.

Molecular and Translational Vascular Medicine will be of great value to a broad audience including internists, cardiovascular and vascular surgeons, pathologists, residents and fellows, as well as translational biomedical researchers.



Jonathon W. Homeister, MD, PhD

McAllister Heart Institute, The University of North Carolina School of Medicine, Chapel Hill, NC, USA

Monte S. Willis, MD, PhD

McAllister Heart Institute, The University of North Carolina School of Medicine, Chapel Hill, NC, USA


Molecular and Translational Vascular Medicine will serve as a state-of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of vascular medicine. The text provides new insight into the basic mechanisms of classic vascular pathophysiologic processes like angiogenesis, atherosclerosis, thrombosis, and vasculitis. Furthermore, it covers new areas of investigation including the role of the ubiquitin proteasome system in vascular disease, endothelial progenitor cells for disease treatment, and the genetic basis of thoracic aortic aneurysms. Lastly, this volume includes sections on the newly emerging field of therapeutic angiogenesis, and the developing technology of nanoparticle-based imaging and therapeutic treatment of the diseased vasculature. All chapters are written by established experts in their fields, including pathologists, cardiovascular surgeons, and internists as well as translational biomedical researchers in a wide range of disciplines. While comprehensive, the material is presented in a manner that simplifies the complex pathophysiologic mechanisms that underlie common vascular diseases. Molecular and Translational Vascular Medicine will be of great value to a broad audience including internists, cardiovascular and vascular surgeons, pathologists, residents and fellows, as well as translational biomedical researchers.

Jonathon W. Homeister, MD, PhDMcAllister Heart Institute, The University of North Carolina School of Medicine, Chapel Hill, NC, USAMonte S. Willis, MD, PhDMcAllister Heart Institute, The University of North Carolina School of Medicine, Chapel Hill, NC, USA

Section 1:  Recent advances in understanding and imaging the molecular and genetic basis of vascular diseases.Ch. 1- The Molecular Biology and Genetics of AneurysmsHelena KuivaniemiGerard C. TrompDavid J. CareyJames R. ElmoreCh. 2- The Molecular Biology and Treatment of Systemic Vasculitis in ChildrenDespina Eleftheriou Paul A. BroganCh. 3- Recent Insights into the Molecular and Cellular Contributions to Venous ThrombosisPeter K. HenkeJose Antonio Diaz Daniel D. Myers, Jr.Thomas W. WakefieldCh. 4- The Ubiquitin Proteasome System in Endothelial Cell Dysfunction and Vascular DiseaseNajeeb A. ShirwanyMing-Hui ZouCh. 5- Molecular Imaging of Vascular Inflammation, Atherosclerosis, and Thrombosis Dan Jane-witMehran M. SadeghiSection 2: The therapeutic potential of angiogenesis, nanomedicine, and endothelial progenitor cells in the treatment of vascular diseaseCh. 6- Molecular Regulation of Vasculogenesis and Angiogenesis:  Recent Advances and Future DirectionsGeorge E. DavisCh. 7- Therapeutic Angiogenesis for Critical Limb Ischemia: Complex Mechanisms and Future ChallengesYihai CaoCh. 8- Modulating the proliferative response to treat restenosis after vascular injury Vicente Andrés GarcíaJosé Javier Fuster Carlos Silvestre Roig Rainer WesselyCh. 9- Cardiovascular Nanomedicine: Challenges and OpportunitiesBiana GodinYe Hu Saverio La FrancescaMauro FerrariCh. 10- Endothelial Progenitor Cells in the Treatment of Vascular DiseaseGareth J. Padfield

Erscheint lt. Verlag 28.6.2012
Reihe/Serie Molecular and Translational Medicine
Molecular and Translational Medicine
Zusatzinfo XIV, 338 p.
Verlagsort Totowa
Sprache englisch
Themenwelt Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Studium 2. Studienabschnitt (Klinik) Pathologie
Naturwissenschaften Biologie
Sozialwissenschaften Politik / Verwaltung
Technik
ISBN-10 1-61779-906-8 / 1617799068
ISBN-13 978-1-61779-906-8 / 9781617799068
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